摘要
作为一种半胱氨酸蛋白酶抑制剂的胱抑素C,其表达失衡是动脉粥样硬化发生与发展的重要原因之一近年来很多研究提示它可能参与了心脑血管疾病的病理过程,可能与神经细胞失调和神经元损伤有关。进一步研究还表明,胱抑素C可能是急性脑梗死等脑血管疾病发生、发展的独立危险因素,推测相关机制与其参与血管损伤及炎症反应等过程有关。
Cystatin C is a Cysteine proteinase inhibitor, and the disequilibrium of its expression is one of the important reasons for the atherosclerotic occurrence and development. Recently, a lot of studies display that Cystatin C is likely to participate in the pathologic processes of the cadiovascular and eerebrovascular diseases, and maybe it relates to the disequilibrium of nerve cells and the injuries of neuron. The further researches have shown that Cystatin C may be an independent risk factor of the cerebrovascular diseases such as acute cerebral infarction, and it may be related to involving in vascular injury and inflammation.
出处
《中华脑血管病杂志（电子版）》
2009年第6期27-31,共5页
Chinese Journal of Cerebrovascular Diseases(Electronic Edition)
关键词
胱抑素C
脑血管疾病
Cystatin C
Cerebrovaseular Diseases
