摘要
目的研究2型糖尿病对骨质疏松发病率的影响及骨质疏松与年龄、体重指数及糖尿病的相关性。方法①选择102例2型糖尿病患者及148例对照组病例,测量其骨密度(BMD)值,采用病例对照法分析2型糖尿病对骨质疏松发病率的影响;②运用Logistic多元回归的方法分析糖尿病、年龄、性别及体重指数对骨质疏松的影响;③对糖尿病、年龄、体重指数与骨质疏松的相关性进行分析。结果①2型糖尿病组的骨质疏松发病率高于对照组,分别为55.9%和43.2%;②骨质疏松与年龄及糖尿病正相关,与体重指数负相关;糖尿病、性别、年龄及体重指数对骨质疏松的影响均有统计学意义;③糖尿病组的年龄、体重指数与骨质疏松的相关性均有统计学意义;而对照组只有年龄有其统计学意义;⑤Ward's三角区为骨质疏松的好发部位。结论①2型糖尿病是骨质疏松的重要影响因素;②2型糖尿病人应保持适当的体重指数;③中老年人均应定期检查BMD,以求尽早诊治骨质疏松和预防其并发症的发生。④Ward's三角区可作为早期诊断骨质疏松的首选检查部位。
Objective To investigate the effect of type 2 diabetes mellitus on incidence of osteoporosis and the correlation of osteoporosis with age,body mass index （BMI） and diabetes. Methods 1 ） The patients with type 2 diabetes mellitus of 102 cases and control patients of 148 cases were selected to measure the Bone Mineral Density（BMD） , and the case-control study was used to analyze the effect of type 2 diabetes meUitus on incidence of osteoporosis; 2 ） The logistic multiple regression was used to analyze the influence of diabetes, age, sex and BMI on osteoporosis; 3 ） The correlation analysis of diabetes, age, BMI and osteoporosis was performed. Results 1 ） The group of type 2 diabetes mellitus had a higher osteoporosis incidence than the control group, ie. 55.9% and 43.2%, respectively; 2） The positive correlation of osteoporosis with age and diabetes was found out, with its negative correlation with BMI; the effect of diabetes, age, sex and BMI on osteoporosis had a statistical significance; 3 ） In the group of diabetes, the correlation of age and BMI with osteoporosis had a statistical significance, but in the control group, only age had a statistical osteoporosis relevance. 4 ） The Ward＇s Triangle Area was the predilection site of osteoporosis. Conclusions 1 ）The type 2 diabetes mellitus is an important risk factor; 2）The patients with type 2 diabetes mellitus should maintain a proper BMI; 3 ） The regular examination of BMD should be performed for the middle-aged and elderly people in order to treat osteoporosis and prevent its complications. 4） The Ward＇s triangle area was regarded as the first choice of examination for early diagnosis of osteoporosis.
出处
《中国骨质疏松杂志》
CAS
CSCD
2010年第5期344-346,共3页
Chinese Journal of Osteoporosis
关键词
2型糖尿病
骨质疏松
骨密度
Type 2 diabetes mellitus
Osteoporosis
Bone mineral density
