摘要
目的调查某院围术期预防性使用抗菌药物的基础数据,为医院实施监控措施、采取临床干预提供科学依据。方法根据事先设计好的调查表,按统一方法和标准,调查分析2008年胆囊切除、乳腺手术、结肠切除和髋关节置换4种手术患者预防手术部位感染抗菌药物使用情况。结果髋关节置换术有约50.00%未在麻醉诱导期预防性使用抗菌药物;而手术时间>3 h有约85.00%在术中未追加抗菌药物;术后使用抗菌药物约80.00%均>24 h;60.50%乳腺手术使用喹诺酮类抗菌药物预防手术部位的感染。结论为减少耐药菌株产生,降低患者、社会的经济负担,控制医院感染,规范围术期抗菌药物的合理使用迫在眉睫,应制定完善的围手术期抗菌药物合理应用管理策略,探索围术期抗菌药物合理应用管理的一种有效的、可行的模式。
OBJECTIVE To obtain a hospital perioperative preventive use of antimicrobial drugs based on data for the state to provide the scientific basis for clinical intervention. METHODS According to pre-designed questionnaire, uniform standards, the investigation of cholecystectomy, breast surgery, colon resection, and hip replacement surgery were found to prevent surgical site infection in patients with the use of antimicrobial agents in a hospital in 2008. RESULTS It indicated that hip replacement surgery was nearly 50.0~/~ without prophylactic use of antimicrobial drugs in the induction of anesthesia, about 85.0 % of the operation time more than three hours was not an additional antimicrobial agents in the surgeryand 80.0 % of postoperative use of antibiotics were more than 24 hours. 60.50% of breast surgery used Fluoroquinolones to prevent surgical site infection. CONCLUSIONS To reduce the resistant strains, lower the economic burden of the patients, control the hospital infection and regulate scope of operation of the rational use of antimicrobial agents are urgent. We should formulate a comprehensive perioperative rational use of antibiotics management strategies to explore an effective, workable model of perioperative antibiotics reasonable application of the management.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2010年第12期1779-1781,共3页
Chinese Journal of Nosocomiology
关键词
手术部位感染
围术期
抗菌药物
Surgical site infection
Perioperative
Antibiotics
