摘要
目的比较垂体后叶素与生长抑素治疗食管-胃底静脉曲张破裂出血的经济效果。方法将100例食管-胃底静脉曲张破裂出血患者随机分成A、B 2组,分别给予垂体后叶素或生长抑素5-10 d,并进行药物经济学评价,采用药物经济学原理对不同治疗方案进行成本-效果分析。结果 A组、B组治疗上消化道出血成本分别为（110.5±20.6）元/人和（751.8±182.5）元/人,2组比较有显著性差异（P〈0.05）;2组有效率分别为84%和90%,2组比较无显著性差异（P〉0.05）;2组成本-效果比分别为156.07±22.7和1 038.1±242.4,2组比较有显著性差异（P（0.05）;2组不良反应发生率分别为26%和8%,2组比较有显著性差异（P〈0.05）。结论从药物经济学角度分析,垂体后叶素治疗肝硬化食管胃底静脉曲张出血较生长抑素更为经济。
Objective It is to evaluate the economic effects of pituitrin and somatostatin in treating the esophageal and gastric variceal bleeding.Methods 100 patients with esophageal and gastric variceal bleeding were divided into 2 groups,the patients were treated for 5~10 days by pituitrin in group A and by somatostatin in group B.The cost and effective of two kinds of treatments with pituitrin and somatostatin were analyzed by economic principle of pharmacology.Results The cost of group A and group B were（110.5±20.6） Yuan and（751.8±182.5） Yuan respectively,with significant difference（P〈0.05）,the effective rates were 84% and 90% respectively,with no significant difference（P〉0.05）,the cost-effective rate were 156.07±22.7 and 1038.1±242.4 respectively,with significant difference（P〈0.05）,and the side effect were 26% and 8% respectively,with significant difference（P〈0.05）.Conclusion Pituitrin is an economical and effective choice in treating hepatic cirrhosis complicated with esophageal and gastric variceal bleeding.
出处
《现代中西医结合杂志》
CAS
2010年第18期2217-2218,2220,共3页
Modern Journal of Integrated Traditional Chinese and Western Medicine
关键词
肝硬化
上消化道出血
垂体后叶素
生长抑素
成本-效果分析
食管-胃底静脉曲张
hepatic cirrhosis
upper gastrointestinal bleeding
pituitrin
somatostatin
cost-effective analysis
esophageal and gastric variceal bleeding
