摘要
研究了黄连解毒汤对人工感染传染性法氏囊病毒雏鸡的免疫器官和免疫功能的影响。将21日龄的艾维茵雏鸡180只随机分成5组,前4组用传染性法氏囊病毒(IBDV)进行攻毒,攻毒后用黄连解毒汤分别以1.5、1.0、0.5mL/只的用量进行饮水治疗,连续7d,攻毒对照组和空白对照组不作处理。结果表明:法氏囊病毒主要侵害免疫器官胸腺、法氏囊和脾脏,其损伤主要体现为感染后7d时胸腺、法氏囊萎缩,脾脏肿大,与感染对照组相比,给药组患病鸡的胸腺、法氏囊、脾脏等器官的损伤程度显著降低,并且黄连解毒汤治疗Ⅰ组(1.5mL/只)外周血ANAE+T细胞数显著升高,抑制了雏鸡免疫功能的降低和红细胞免疫黏附功能的下降,表明黄连解毒汤对受法氏囊病毒感染的雏鸡的免疫器官和免疫功能具有较好的保护作用。
The experiment was conduted to study the effects of Huanglian Jiedu decoction on immune organ and immune function in chicken. 180 twenty-one-day-old Avian broilers were randomly into five groups. All the therapeutic groups of chickens were medicated for 7 successive days drinking water with Huanglian Jiedu decoction （1.5,1.0,0.5 mL/single）,respectively,the other group was unmedicated as infected control.The results showed that IBDV mainly injured the bursa,thymus and spleen. The pathological changes after infection for seven days were that strains could cause severe atrophy of the busra and thymuses,and swell up of the spleen. There was a marked decline in pathological changes of the infected chicken’s thymuse, bursa, spleen, and the ANAE＋ ratio of peripheral blood lymphocytes in Huanglian Jiedu decoction Ⅰgroups （1.5 mL/single）when compared with infective control.The above mentioned results indicated that immune organ and immune function in chicken infected with IBDV were protected by Huanglian Jiedu decoction
出处
《广东农业科学》
CAS
CSCD
北大核心
2010年第5期135-137,共3页
Guangdong Agricultural Sciences
基金
河北省科技厅科技支撑项目(09240419D)
关键词
黄连解毒汤
雏鸡
免疫功能
免疫器官
Huanglian Jiedu decoction
chicken
immune function
immune organ
