摘要
目的:总结扬州某三甲医院2009年度药物引起的不良反应,促进临床合理用药。方法:对扬州某三甲医院2009年度收集到的308例ADR报告进行回顾性汇总分析。结果:经静脉给药引发的ADR有290例,占94.16%;抗菌药物的ADR发生率最高,有270例,占87.66%;ADR的临床表现以皮肤系统损害最为常见,有181例,占58.77%,经过相应的治疗均恢复正常。上报的ADR大部分为已知的、轻度的ADR,其中多数对原患疾病无明显影响。结论:该院发生ADR最多的是抗菌药物,其中以头孢菌素类占首位,提示临床根据患者具体情况,合理使用抗生素;ADR的临床表现以皮肤损害为主;联合用药应注意配伍禁忌。用药前要询问患者的过敏史,用药后认真观察,减少不良反应发生。
Objective： To promote clinical rational drug use through summarizing adverse drug reactions（ADR） in a top three hospital of Yangzhou in 2009. Methods：308 ADR cases collected in a top three hospital in 2009 were analyzed by retrospective analysis.Results：Of the total ADR cases,290 were administrated by injection, occupied 94. 16%;270 cases were associated with anti-infective which had the highest rate accounting for 87.66%. 181ADR cases（58. 77%） had rash and inching of skin which were the most common manifestations.The damage could be cured by appropriate treatment. The most reprots which had not obvious effect on primary disease were known and mild. Conclusion： Most ADR cases were associated with antibiotics especially cephalospiorins, suggesting that the rational use of antibitics should consider the specific eonditons of patients.Tbe most common manifestations of ADR were damage of skin. Attention should be payed to incompatibility in combination threapy.Tbe history of allergic should be inquired before treatment. Close observation is needed after treatment to reduce adverse reactions.
出处
《黑龙江医药》
CAS
2010年第3期379-382,共4页
Heilongjiang Medicine journal
关键词
药品不良反应
报告
回顾性分析
Adverse drug reaction
Report
Retrospective analysis
