摘要
目的:比较刺络疗法与西药强的松治疗过敏性紫癜性肾炎的疗效差异。方法:将70例紫癜性肾炎急性肾炎综合征型患者随机分为观察组(40例)和对照组(30例)。观察组分实证和虚证,实证采用三棱针点刺合谷、曲池、血海等穴,虚证采用毫针浅刺脾俞、肾俞、足三里等穴;对照组口服西药强的松治疗,观察两组治疗前后中医症状积分、24 h尿蛋白定量、尿沉渣红细胞数的变化,并比较两组疗效。结果:观察组总有效率为92.5%(37/40),优于对照组的80.0%(24/30),组间比较差异有统计学意义(P<0.05);两组治疗后中医症状积分、24 h尿蛋白定量、尿沉渣红细胞数均显著改善(均P<0.05),且观察组的改善程度优于对照组(均P<0.05);治疗后观察组中实证组中医症状积分低于虚证组(P<0.05)。结论:刺络疗法治疗过敏性紫癜性肾炎疗效显著,明显优于口服强的松治疗,且实证疗效优于虚证。
Objective To compare the difference of therapeutic effects between vessel pricking therapy and Prednisone for treatment of henoch-schonlein purpura nephritis. Methods Seventy cases of acute purpura nephritis syndrome were randomly divided into an observation group （40 cases） and a control group （30 cases）. Patients in observation group were differentiated into sthenia and asthenia syndromes. Vessel pricking therapy was applied at Hegu （LI 4）, Quchi （LI 11）, Xuehai （SP 10） etc. by triangular needle for sthenia symptom~ shallow needling was used at Pishu （BL 20）, Shenshu （BL 23）, Zusanli （ST 36） etc. by filiform needle. The control group was treated with oral admi-nidtration of Prednisone. The symptom score of TCM, 24 h urinary protein, red blood cell count of urinary sediment of both groups were observed before and after treatment and therapeutic effects were compared. Results The total effective rate of 92.5%（37/40） in observation group was superior to that of 80.0%（24/30） in control group, and there was a significant difference between two groups （P〈0.05） ; the symptom score of TCM, 24 h urinary protein, red blood cell count of urinary sediment were all improved in both groups after treatment （all P〈0.05）, and moreover, the improvement in observation group was superior to that of control group （all P〈0.05） ; after treatment, the symptom score of TCM of sthenia syndrome was lower than that of asthenia syndrome in observation group （P〈0.05）. Conclusion Vessel pricking therapy has a significant therapeutic effect for treatment of henoch-schonlein purpura nephritis, superior to that of oral administration of Prednisone, and the therapeutic effect is better for treating sthenia syndrome than for asthenia syndrome.
出处
《中国针灸》
CAS
CSCD
北大核心
2010年第6期449-452,共4页
Chinese Acupuncture & Moxibustion
基金
河北省中医药管理局立项课题项目:2009128
关键词
紫癜性肾炎
刺络疗法
随机对照试验
Henoch-Schonlein Purpura Nephritis
Vessel Pricking Therapy
Randomized Controlled Trials （RCT）
