摘要
实验研究鸭胚多肽对小鼠机体抗疲劳、耐缺氧能力的影响。实验设对照组和实验组(鸭胚多肽低剂量、中剂量和高剂量组),连续灌胃小鼠30 d后,测定小鼠负重游泳力竭至死时间,并测定小鼠游泳后血清中乳酸(LD)含量、尿素氮(BUN)含量、葡萄糖(LG)含量、乳酸脱氢酶(LDH)活性,小鼠常压耐缺氧存活时间、亚硝酸钠中毒存活时间、急性脑缺血性存活时间。结果表明:鸭胚多肽能显著增加小鼠负重游泳时间、血清中LDH活性、小鼠亚硝酸钠中毒存活时间及急性脑缺血性存活时间,并能显著降低LD、BUN含量。说明鸭胚多肽能有效提高小鼠的抗疲劳、耐缺氧能力。
Experimental observation of the effects of duck embryo pepfides on the ability of mice anti-fafigue,anfi-anoxia and anti- oxidation. All of the mice were divided into two groups, each consisting established control group and experimental group （ duck embryo peptides low-dose, medium-dose and high-dose group）, Gavage for 30 days. The loadedswimming time was recorded, the contents of LD, BUN, LG in serums, the survival time of mice under closed normobaric hypoxia,nitrite toxicosis and being afflicted with acute cerebral ischemia, the activities of LDH were measured respectively. The results showed that duck embryo peptides can be significantly increased in mice loaded-swimming time, the activities of LDH in serums ,the survival time of mice under nitrite toxicosis and being afflicted with acute cerebral ischemia, significantly decreased the contents of LD,BUN in serums. It is concluded that duck embryo peptides can impreve the ability of anti-fatigue, anti-anoxia of mice.
出处
《天然产物研究与开发》
CAS
CSCD
2010年第3期502-505,共4页
Natural Product Research and Development
关键词
鸭胚肽
抗疲劳
耐缺氧
duck embryo peptides
anti-fatigue
anti-anoxia
