摘要
目的：本文旨在探讨急进高原低氧人群血浆ＮＯ和红细胞ＳＯＤ的变化及其相互作用的生理意义。方法：以急进高原的健康人群为研究对象，年龄范围在１８～２１岁之间，分为对照组和高原低氧组。血浆ＮＯ测定采用硝酸还原酶法，红细胞ＳＯＤ测定采用亚硝酸盐显色法。结果：高原低氧组血浆ＮＯ浓度显著低于平原对照组；高原低氧组红细胞ＳＯＤ含量显著高于平原对照组。结论：急进高原低氧人群红细胞ＳＯＤ显著升高，ＮＯ降低，可能与低氧造成肺血管收缩有关系。但ＮＯ、自由基及自由基清除剂（ＳＯＤ）之间的调控网络。
Aim: To study the changes and physiological interaction of plasma nitric oxide (NO)
and red blood cell superoxidase (SOD) of people entered rapidly into high altitude of 3658m.
Methods: The subjects aged between 18 and 21 were healthy and divided into control and
hypoxia groups, plasma NO was measured by nitric acid reductase and red blood cell SOD, by
nitrat coloration. Results: The plasma NO concentration of the hypoxia group was lower
significantly than that of the control ( P <0.05) but its red blood cell SOD contents were much
higher than the latter ( P <0.05). Conclusion:The increase of red blood cell SOD and the
decrease of plasma NO concentration in people entered to high altifude may be related to the
contraction of pulmonary artery due to hypoxia.
出处
《中国应用生理学杂志》
CAS
CSCD
1999年第1期47-49,共3页
Chinese Journal of Applied Physiology
基金
中国人民武装部队警医学院科研基金
