摘要
目的观察慢性乙型肝炎(简称乙肝)患者血清C反应蛋白(CRP)、甲胎蛋白(AFP)、癌胚抗原(CEA)、糖类抗原CA19-9的变化,探讨其在临床诊断中的应用价值。方法采用化学发光法检测AFP、CEA、CA19-9,免疫透射比浊法检测CRP。结果慢性乙肝患者血清CRP、AFP、CEA、CA19-9含量显著高于健康对照组(P<0.01)。4项指标联合检测在各组中的阳性率明显高于单一指标的阳性率,差异有统计学意义(P<0.005)。结论 CRP、AFP、CEA、CA19-9检测不仅能提高慢性乙肝的检出率,而且根据其血清水平能判断病情的严重程度。
Objective To observe serum CRP,AFP,CEA,CA19-9 in the patients with chronic hepatitis B and to explore their clinical diagnosis.Methods Chemiluminescence was used to detected AFP,CEA,CA19-9,CRP was detect by the immune turbidimetric.Results In the chronic hepatitis B group,CRP,AFP,CEA,CA19-9 levels were significantly higher than those in the normal control group（P〈0.01）. The positive rate by joint detection of four targets was significantly higher than that by single indicator（P〈0.005）.Conclusion CRP,AFP,CEA and CA19-9 detection can not only improve the detection rate of chronic hepatitis B,but also determine the severity of illness.
出处
《检验医学与临床》
CAS
2010年第13期1297-1298,共2页
Laboratory Medicine and Clinic
