摘要
目的探讨内镜下逆行胰胆管造影(ERCP)术后引发急性胰腺炎(PEP)的危险因素,为PEP的预防和治疗提供参考。方法对84例行ERCP检查或治疗的胆胰疾病患者的临床资料进行回顾性分析,对PEP发生的相关危险因素进行Logistic回归分析,筛选PEP发生的相关危险因素。结果 ERCP术后并发PEP5例,发病率为5.95%。单因素分析结果显示,既往有胰腺炎病、多次插管、胰管多次显影、导丝多次进入、导丝引导插管、全胰管显影、术中腹痛与PEP发生有关(P<0.05),而PEP发病与女性、诊断性ERCP、治疗性ERCP、乳头括约肌切开等无明显相关性(P>0.05);多因素Logistic回归法分析表明多次插管、既往有胰腺炎和胰管多次造影是PEP发生的危险因素。结论多次插管、既往有胰腺炎和胰管多次造影是PEP发生的危险因素,对这些危险因素加以重点评估和合理控制,可以控制PEP的发生。
[Objective]To investigate the risk factors of acute pancreatitis after ERCP,and provide reference for prevention and treatment of acute pancreatitis after ERCP.[Methods]The clinical data of 84 cases of patients with biliary and pancreatic diseases by ERCP examination and treatment were retrospectively analyzed, the risk factors of incidence of acute pancreatitis after ERCP were analyzed and screened by logistic.[Results]The incidence rate of acute pancreatitis after ERCP was 5.95% . The single-factor analysis showed that those who suffered from pancreatitis, multiple cannulation, repeated pancreatic duct imaging, guide wire repeatedly into the pancreas, guide wire to guide intubation, all pancreatic duct imaging and intraoperative abdominal pain had certain degree of contact with acute pancreatitis after ERCP. The female, diagnostic ERCP, therapeutic ERCP, sphincterotomy were no significantly correlated with incidence of acute pancreatitis after ERCP. Multivariate Logistic regression analysis showed that multiple cannulation, suffered from pancreatitis and repeated pancreatic duct imaging were risk factors of incidence of acute pancreatitis after ERCP （P〈0.05）. [Conclusion]The multiple cannulation, suffered from pancreatitis and repeated pancreatic duct imaging are the risk factors of incidence of acute pancreatitis after ERCP, assessment and control of these risk factors can reduce incidence of acute pancreatitis after ERCP.
出处
《中国内镜杂志》
CSCD
北大核心
2010年第5期462-464,468,共4页
China Journal of Endoscopy
