摘要
目的评价左卡尼汀联合疏血通注射液治疗不稳定型心绞痛病人的临床疗效及安全性。方法将50例不稳定型心绞痛病人随机分为对照组和治疗组各25例;两组均常规给予硝酸酯类,β受体阻断剂,抗凝,抗血小板聚集等常规治疗,其中治疗组在常规治疗的基础上给予左卡尼汀及疏血通注射液,两组治疗疗程均14天;并观察治疗前后患者的症状体征、心电图、血清C-反应蛋白(CRP)、血液流变学的变化。结果治疗后治疗组总有效率92%,对照组总有效率80%,两组比较,差异显著(P<0.05);CRP显著下降,与对照组比较,差异显著P<0.05;血液流变学指标明显改善,与对照组比较,P<0.05。结论左卡尼汀联合疏血通注射液治疗不稳定型心绞痛疗效肯定,且不良反应少,是一种安全有效的方法,值得临床推广。
Objective To evaluate the curative effect and safety of Levocarnitine injection with Shuxuetong injection in patients with unstable angina(UA).Methods 50 patients with UA were randomly divided into two groups: Routine treatment group(n=25) and treatment group(n= 25).Patients in treatment group were treated with Nitrate,β-receptor blocking pharmacon,anticoagulation,anti platelet aggregation et al.Patients in treatment group were treated with levocarnitine injection and Shuxuetong injection and routine treatmentBefore and after treatment,the symptom and signs,electrocardiogram,C-reactive protein and hemorrheologic were observed.Results The total effective rate of treatment group and routine group was 92% and 80%,respectively(P〈0.05).After treatment,the CRP in treatment group was decreased significantly,compared with that in the routine treatment group.Conclusion Combination therapy of levocarnitine injection with Shuxuetong injection can effectively control UAP.
出处
《西部医学》
2010年第7期1250-1252,共3页
Medical Journal of West China
关键词
左卡尼汀注射液
疏血通注射液
不稳定型心绞痛
疗效
Levocarnitine injection
Shuxuetong injection
Unstable angina pectoris
Curative effect