期刊文献+

胃肠道间质瘤65例诊治分析

原文传递
导出
摘要 目的探讨胃肠道间质瘤(GIST)的临床病理特征及诊断治疗方法。方法回顾性分析2004-01-2009-12收治的65例GIST患者的临床和病理资料。结果 65例GIST患者中,胃31例,十二指肠6例,小肠17例,结直肠7例,腹膜后或原发不明4例。均经病理和免疫组化明确诊断。全组均行手术治疗,3例出现胃排空障碍,2例出现腹腔感染,1例出现胰瘘,经保守治疗后恢复。无手术死亡病例。结论 GIST患者临床症状缺乏特异性,易误诊、漏诊,病理及免疫组化是诊断胃肠道间质瘤的必要手段,手术整块切除是治愈GIST的惟一首选方法。
出处 《中国误诊学杂志》 CAS 2010年第22期5458-5459,共2页 Chinese Journal of Misdiagnostics
  • 相关文献

参考文献4

  • 1Miettinen M , I.asota J . Gastrointestinal stromal tumors: review on morphology , molecular pathology prognosis, and differential diagnosis [J]. Arch pathol Lab Med,2006,130(10): 1466-1478.
  • 2李斯润,陈永标,林华.胃间质瘤27例的诊治分析[J].重庆医学,2008,37(17):1974-1975. 被引量:7
  • 3Raut CP, Ashley SW, How I do it:surgical management of gastrointestinal stromal tumors[J]. J Gastrointest Surg, 2008, 12 (9) : 1592-1599.
  • 4娄越亮,陈华,张燮良,战忠利.96例胃肠道间质瘤临床诊治分析[J].中华肿瘤杂志,2004,26(7):437-439. 被引量:25

二级参考文献17

  • 1Emory TS, Sobin LH, Lukes L, et al. Prognosis of gastrointestinal smooth-muscle (stromal) tumors: dependence on anatomic site. Am J Surg Pathol, 1999,23:82-87.
  • 2DeMatteo RP, Lewis JJ, Leung D, et al. Two hundred gastrointestinal stromal tumors: recurrence patterns and prognostic factors for survival. Ann Surg, 2000,231:51-58.
  • 3Miettinen M, Lasota J. Gastrointestinal stromal tumors-definition, clinical, histological, immunohistochemical, and molecular genetic features and differential diagnosis. Virchows Arch, 2001,438:1-12.
  • 4Fletcher CD, Berman JJ, Corless C, et al. Diagnosis of gastrointestinal stromal tumors: a consensus approach. Hum Pathol, 2002,33:459-465.
  • 5Kindblom LG, Remotti HE, Aldenborg F, et al. Gastrointestinal pacemaker cell tumor (GIPACT): gastrointestinal stromal tumors show phenotypic characteristics of the interstitial cells of Cajal. Am J Pathol, 1998,152:1259-1269.
  • 6Taniguchi M, Nishida T, Hirota S, et al. Effect of c-kit mutation on prognosis of gastrointestinal stromal tumors. Cancer Res, 1999,59:4297-4300.
  • 7Demetri GD. Identification and treatment of chemoresistant inoperable or metastatic GIST: experience with the selective tyrosine kinase inhibitor imatinib mesylate (STI571). Eur J Cancer, 2002,38 Suppl 5:S52-S59.
  • 8Ng EH, Pollock RE, Munsell MF, et al. Prognostic factors influencing survival in gastrointestinal leiomyosarcomas. Implications for surgical management and staging. Ann Surg, 1992,215:68-77.
  • 9Demetri GD, von Mehren M, Blanke CD, et al. Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors. N Engl J Med, 2002,347:472-480.
  • 10Mzaur MT,Clark HB. Gastric stromal tumors, reappraisal of histogenesis[J]. Am J Surg Pathol, 1983,7(60) :507.

共引文献30

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部