摘要
目的:观察板蓝根不同提取物抗甲型流感病毒的作用。方法:采用血凝滴度640以上的甲型流感病毒A/PR/8/34的尿囊液30μl滴鼻感染小鼠,观察小鼠感染甲型流感病毒后发病及死亡情况。结果:板蓝根提取物2号1.0g/kg剂量组和板蓝根提取物3号1.67g/kg剂置组可明显延长甲型流感病毒感染小鼠存活天数和降低死亡率与病毒对照组比较具有显著性差异(P<0.05,P<0.01)。板蓝根提取物1号0.67g/kg剂量组和板蓝根提取物4号1.12g/kg剂量组可明显延长甲型流感病毒感染小鼠存活天数,与病毒对照组比较具有显著性差异(P<0.05)。结论:板蓝根提取物2号组和板蓝根提取物3号组具有较好的抗甲型流感病毒的作用。
Objective： Observed the effect of different extracts of Radix Anti-influenza virus A. Methods：Used hemagglutination titer of more than 640 influenza A virus A/PR/8/34 30μl allantoic fluid intranasally infected mice, observed mice infected with influenza A virus morbidity and mortality, Results：The extract of Radix 2, 1.0 g / kg dose group and The extract of Radix 3 1.67g/kg dose can prolong the survival of mice infected with influenza virus A and reduce mortality, was significant differences of the virus control group （P 〈0.05, P 〈0.01）. The extract of Radix 1 0.67g/kg dose group and The extract of Radix 4 1.12g/ kg dose can prolong the survival of influenza A virus infection in mice, was significant differences of the virus control group （P 〈0.05） . Conclusion： The extract of Radix 2 group and The extract of Radix 3 group has good resistance to influenza virus A.
出处
《中国医药导刊》
2010年第6期1003-1004,共2页
Chinese Journal of Medicinal Guide
