期刊文献+

帕瑞昔布钠用于胸腔镜手术病人超前镇痛的临床观察 被引量:2

在线阅读 下载PDF
导出
摘要 目的研究帕瑞昔布钠超前镇痛对胸腔镜手术病人术后镇痛效果的影响。方法选择行胸腔镜60例患者,随机分成帕瑞昔布钠治疗组和生理盐水对照组,治疗组分别于切皮前30min和术毕静脉注射帕瑞昔布钠40mg作为超前镇痛,对照组于相同时点静脉注射生理盐水2mL。术后行疼痛评分及不良反应的观察。结果治疗组术后1、4、8、12h,VaS评分显著低于对照组(P<0.01),24h两组差异无显著性。结论帕瑞昔布钠治疗组超前镇痛可以产生较好的术后镇痛效果,不良反应少,可有效减少术后阿片类药物的使用量。
出处 《海峡药学》 2010年第7期142-143,共2页 Strait Pharmaceutical Journal
  • 相关文献

参考文献2

二级参考文献11

  • 1McArdle P. Intravenous analgesia. Crit Care Clin, 1999,15:89-104.
  • 2Bowdle TA. Adverse effects of opioid agonists and agonist-antagonists in anesthesia. Drug Saf, 1998,19:173-189.
  • 3Kehlet H, Dahl JB. The value of "multimodal" or "balanced analgesia"in postoperative pain treatment. Anesth Analg, 1993,77:1048-1056.
  • 4Power I, Barrett S. Analgesic agents for the postoperative period: nonopioids. Surg Clin North Am, 1999,79:275-295.
  • 5Tong D, Chung F. Postoperative pain control in ambulatory surgery. Surg Clin North Am, 1999,79:401-430.
  • 6Lipsky LP, Abramson SB, Crefford L, et al. The classification of cyclooxygenase inhibitors. J Rheumatol, 1998,25:2298-2303.
  • 7Penning TD, Talley JJ, Berteushaw SR, et al. Synthesis and biological evaluation of the 1,5-diarylpyrazole class of cyclooxygenuse-2 inhihitors:identification of 4- [ 5- ( 4-methylphenyl ) -3- ( trifluoremethyl )- 1H-pyrazol-1-yl]benze nesulfonamide (SC-58635, celecoxib). J Med Chem, 1997,40:1347-1365.
  • 8Tang J, Li S, White PF, et al. Effect of parecoxib, a novel intravenous cyclooxygenuse type-2 inhibitor, on the postoperative opioid requirement and quality of pain control. Anesthesiology, 2002,96: 1305-1309.
  • 9Malan TP Jr,Marsh G, Hakki SI, et al. Parecoxib sodium, a parenteral cyclooxygenuse 2 selective inhibitor, improves morphine analgesia and is opioid-sparing following total hip arthroplasty. Anesthesiology, 2003,98 :950-956.
  • 10Kranke P, Morin AM, Roewer N, et al. Patients' global evaluation of analgesia and safety of injected parecoxib for postoperative pain: a quantitative systematic review. Anesth Analg, 2004,99:797-806.

共引文献366

同被引文献20

引证文献2

二级引证文献11

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部