摘要
早期诊断非酒精性脂肪性肝病(NAFLD)对防治糖尿病和心血管疾病有重要意义.定性检查方法灵敏度和特异性不一,且无法满足定量之需.病理诊断虽然可以定量,但其有创性限制了临床应用.1H磁共振波谱(1H MRS)定量技术的建立,为无创测定肝脏脂肪含量开辟了新的途径.本文综述了NAFLD无创诊断方法新进展.
An early diagnosis of nonalcoholic fatty liver disease ( NAFLD) is meaningful to the prevention and cure of diabetes and cardiovascular disease ( CVD). The sensitivity and specificity of qualitative methods vary greatly, and these methods do not quantify liver fat content. Pathological diagnosis is a quantitative method, but it is invasive and inappropriate for clinical application. The establishment of H Magnetic Resonance Spectrum (1H MRS) opened up a brand-new era for noninvasive liver fat quantification. This review systemically introduces the new progress in noninvasive diagnosis of NAFLD.
出处
《中华内分泌代谢杂志》
CAS
CSCD
北大核心
2010年第7期623-626,共4页
Chinese Journal of Endocrinology and Metabolism
基金
国家十一五科技支撑计划(2008BAI52B03)
上海市卫生局重点学科建设项目(08GWZX0203)
上海市科委基金(08dj1400601)
关键词
脂肪肝
超声
CT
MRI
磁共振波谱
Liver steatosis
Ultrasound
CT
MRI
Magnetic resonance spectroscopy