摘要
目的:探讨脂肪乳注射液所致不良反应的一般规律及特点,为其合理应用提供参考。方法:检索1990年1月～2010年4月的中文医药卫生期刊,对其报道的97例有关脂肪乳注射液不良反应作汇总性统计与分析。结果:脂肪乳注射液致不良反应,临床表现以变态反应为主,其他为脂肪超载综合征、中枢神经系统等不良反应;时间多发于2h以内,以首发型为主。结论:临床工作者应掌握脂肪乳注射液不良反应的特点,安全用药。
OBJECTIVE： To explore the regularity and characteristics of ADR cases induced by Fat emulsion injection, and to provide reference for rational use of it. METHODS： Retrieved from Chinese medical science periodicals from Jan. 1990 to Apr. 2010, 97 ADR cases induced by Fat emulsion injection were analyzed statistically. RESULTS： Main clinical manifestations of ADR cases induced by Fat emulsion injection were allergy reaction, followed by fat overloading syndrome, central nervous system reaction. The majority of ADR cases broke out in the first time of medication within 2 hour. CONCLUSION： It is essential for clinical practitioners to master the characteristics of ADR cases caused by Fat emulsion injection so as to promote safety of drug use.
出处
《中国药房》
CAS
CSCD
北大核心
2010年第32期3038-3040,共3页
China Pharmacy
