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高血压与糖尿病并存对动脉硬化的影响 被引量:1

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摘要 目的比较原发高血压(Hypertension,EH)、2型糖尿病(Type 2 diabetes mellitus,T2DM)、EH合并T2DM对动脉粥样硬化损害的影响强度。方法分别用彩色多普勒超声探测115例原发EH患者(EH组),76例T2DM患者(T2DM组),53例EH合并T2DM患者(EH+T2DM组)及正常健康体检者50例(对照组,Control group,CG)的颈动脉内-中膜厚度(Intima-mediathick-ness,IMT)、是否斑块等指标。结果 (1)EH组和T2DM组IMT、搏动指数(Pulseindex,PI)、阻力指数(Resistanceindex,RI)均大于CG,P<0.01,而EH+T2DM组各参数又高于EH组和T2DM组,P<0.01。(2)ET组、T2DM组、ET+T2DM组和CG斑块检出率分别是50.45%(58/115)、47.37%(36/76)、66.04%(35/53)和26.00%(13/50),P<0.01。斑块积分分别是(1.86±1.54)分、(1.35±1.20)分、(2.83±2.24)分和(0.96±0.71)分,P=0.000,EH+T2DM组积分高于其它3组,P<0.01,EH组又高于T2DM组和CG,P<0.05。结论 EH和T2DM均对动脉产生损害,二者并存时损害程度更严重。
出处 《西南军医》 2010年第5期874-876,共3页 Journal of Military Surgeon in Southwest China
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