摘要
目的评价异甘草酸镁治疗伴高胆红素血症病毒性肝炎的临床疗效。方法将117例伴高胆红素血症病毒性肝炎患者随机分为两组,除普通治疗外,治疗组加用异甘草酸镁治疗,检测两组患者治疗前后血清生化学指标。结果异甘草酸镁治疗伴高胆红素血症病毒性肝炎4周后,治疗组总有效率为82.5%,优于对照组的70.4%(P=0.004);随访4周后,治疗组总有效率为88.9%,明显优于对照组的53.7%(P<0.001)。异甘草酸镁具有抗肝纤维化作用且无明显不良反应。结论异甘草酸镁可以有效治疗伴高胆红素血症的病毒性肝炎。
Objective To evaluate the clinical efficacy of magnesium isoglycyrrhizinate in the management of virus hepatitis with hyperbilirubinemia.Methods 117 patients with virus hepatitis with hyperbilirubinemia were randomly divided into the therapy group and the control group.Besides routine therapy,patients in the therapy group received management of magnesium isoglycyrrhizinate.Serum biochemical parameters were determined in all patients at the onset and end of treatment.Results Four weeks after the treatment,the total effective response was 82.5% in the therapy group and 70.4% in the control group with a significant difference（P=0.004）.After four week follow-up,the total effective response was 88.9% in the therapy group and 53.7% in the control group with a significant difference（P0.001）.The treatment with magnesium isoglycyrrhizinate was effective in reducing liver fibrosis and without significant side effects.Conclusion Magnesium isoglycyrrhizinate is effective for virus hepatitis with hyperbilirubinemia.
出处
《山东大学学报（医学版）》
CAS
北大核心
2010年第8期103-106,共4页
Journal of Shandong University:Health Sciences
关键词
异甘草酸镁
肝炎
病毒性
高胆红素血症
肝纤维化
Magnesium isoglycyrrhizinate
Hepatitis
viral hepatitis
Hyperbilirubinemia
Liver fibrosis
