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超声引导微波消融治疗子宫肌瘤的临床研究 被引量:15

Clinical research on ultrasound-guided microwave ablation therapy for uterine leiomyoma
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摘要 目的:探讨超声引导微波消融(MWA)治疗子宫肌瘤的有效性和安全性。方法:采用ECO-100型微波治疗仪对子宫肌瘤患者14例中共16个肌瘤进行治疗,比较治疗前后患者的超声图像和临床症状的变化,将疗效分为治愈、显效、有效和无效。结果:治疗后1、3、6、12、24个月随访,超声检查显示肌瘤体积较治疗前明显缩小(P<0.01),平均缩小率分别为(47.98±18.66)%、(57.26±16.48)%、(66.82±16.81)%、(79.87±15.04)%、(92.52±8.10)%。子宫肌瘤相关临床症状较治疗前明显改善,14例患者中治愈10例(10/14)、显效2例(2/14)、有效2例(2/14)、无效0例,总有效率为100%。1例患者治疗后出现肠穿孔。结论:MWA治疗子宫肌瘤效果显著,术后患者痛苦小、恢复快,具有良好应用前景及推广价值,值得进一步研究。 Objective:To study the safety and effectiveness of ultrasound-guided microwave ablation(MWA) therapy for uterine leiomyoma.Methods:Fourteen patients with sixteen uterine leiomyomas were chosen for assessment and the mode ECO-100 of microwave therapeutic apparatus was used.The ultrasound images and clinical symptoms before and after the treatment were compared.The results were divided into cured,valid,improved and invalid.Results:The average rates of reduction in leiomyoma volume were 47.98±18.66%,57.26±16.48%,66.82±16.81%,79.87±15.04% and 92.52±8.10%,respectively after MWA 1,3,6,12 and 24 months by evaluation of ultrasound.There was a significant difference in leiomyoma volume between pre-and post-treatment(P〈0.01).The clinical symptoms of all the patients were improved significantly after ablation.Among the patients,10 patients were cured(10/14),2 cases were valid(2/14),2 cases were improved(2/14) and none was invalid(0/14).The total effective rate was 100%.One case of enterobrosis occurred after treatment.Conclusion:The treatment of uterine leiomyoma with MWA is effective and safe.The patients suffer little distress and recover soon after treatment.So the therapy is clinically prospective for application and has a popular value.
出处 《交通医学》 2010年第4期361-363,368,共4页 Medical Journal of Communications
关键词 子宫肌瘤 超声引导 微波消融 Uterine leiomyoma Ultrasound-guided Microwave ablation
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