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人心房组织小电导钙激活钾通道的分子鉴定(英文) 被引量：5

MOLECULAR IDENTIFICATION OF SMALL CONDUCTANCE Ca^(2+)-ACTIVATED K^+ CHANNEL IN HUMAN ATRIAL TISSUE
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摘要 目的:证实人心房组织有SK2的存在。方法:RT-PCR和western-blot分别检测SK2的mRNA和蛋白。结果:RT-PCR检测到人心房组织中存在SK2的mRNA,western-blot检测到SK2的特异性条带。结论:人心房组织存在SK2。 Objective：To confirm the existence of SK2 in human atrial tissue.Methods： RT-PCR and west-ern-blot were used to identify SK2 mRNA and protein.Results： SK2 mRNA was detected by RT-PCR,SK2 pro-tein was detected by western-blot.Conclusion： SK2 is present in human atrial tissue.
作者 李涛 曾晓荣 白志茹 谭晓秋 刘智飞 杨艳
机构地区 泸州医学院心血管医学研究所
出处 《泸州医学院学报》 2010年第4期394-396,共3页 Journal of Luzhou Medical College
基金 Supported by grants from the national natural science foundation of China(NO:30870903)
关键词 SK2 心房组织 人类 SK2 atrial tissue human
分类号 R322.8 [医药卫生—人体解剖和组织胚胎学]
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参考文献12

  • 1Tamarina NA,W.Y,Mariotto L,et al.Small-conductance calcium-activated K+ channels are expressed in pancreatic islets and regulate glucose responses[J].Diabetes,2003;52:2000.
  • 2Taylor MS,B.A,Gross TP,et al.Altered expression of small-conductance Ca2+-activated K+(SK3) channels modulates arterial tone and blood pressure[J].Circ Res,2003; 93:124.
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泸州医学院学报
2010年 第4期

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