摘要
通过夹闭沙土鼠双侧颈总动脉１０ ｍｉｎ 或２０ ｍｉｎ 后再灌７ ｄ 或１ ｄ ， 造成脑缺血再灌模型， 检测血塞通对沙土鼠脑组织钙、水含量的影响， 以及对海马 Ｃ Ａ１ 区死亡的神经元迟发性损伤的保护作用． 结果显示， 血塞通可降低缺血后脑组织钙的含量， 减少海马 Ｃ Ａ１ 区死亡的神经元数量， 增加神经元密度． 实验结果提示血塞通对脑缺血再灌损伤有一定的保护作用．
The model of cerebral ischemia and reperfusion in gerbils was induced by bilateral carotid arteries occluded for 10 min or 20 min follwed by 7-day or 1-day reperfusion. The effect of ginsenoside injection on the content of calcium, water in brain and the density of neuron in hippocampal CA 1 sector was observed. The results showed that ginsenoside injection could decrease the content of calcium in brain and increase the density of neuron in hippocampal CA 1 sector. It suggests that gingenoside injection has a protective effect on cerebral ischemia and reperfusion injury.
出处
《昆明医学院学报》
1999年第2期1-3,共3页
Journal of Kunming Medical College
基金
云南省应用基础研究基金
