摘要
本文研究了在丙酮-水体系中盐酸林可霉素的介稳区性质,建立了介稳区宽度的数学模型。测定了一定条件下的溶解度曲线和超溶解度曲线,为工业生产选择适宜的结晶过饱和度提供了依据。
The meta-stable zone characteristics of lincomycin hydrochloride in acetone-water system were studied, and the mathematical model for meta-stable zone width was proposed. From the experimental data, the solubility curve and supersolubility curve respectively in certain conditions were determined. Results of this study could be used as a basis to provide the selection of optimum conditions for the supersaturated crystallization process.
出处
《中国抗生素杂志》
CAS
CSCD
北大核心
1999年第3期180-183,共4页
Chinese Journal of Antibiotics
关键词
盐酸林可霉素
溶析
结晶
介稳区
Lincomycin hydrochloride
Solventout
Crystallization
Metastable zone