摘要
金属硫蛋白(MT)具有调节生物体内微量元素浓度以及对重金属的解毒作用,对激素的调节,细胞代谢的调节,细胞分化和增殖的控制以及参与紫外(UV)诱导反应和清除自由基都有重要作用。本文就金属硫蛋白的性质、生理功能、提取纯化技术、检测技术等研究进展及应用前景进行综述,以期为其开发应用提供参考依据。
Metallothionein （MT） is a cysteine-rich,highly conserved,low molecular and heavy metal-binding protein,which plays important roles in modulating concentrations of trace elements and detoxification of heavy metals.In addition,MT is also involved in the regulation of hormonal and cell metabolism,the control of cell differentiation and proliferation,UV reaction and the scavenging of free radicals.In this paper,current research progress in the properties,physiological functions,extraction and purification technologies and detection strategies of MT have been reviewed and application prospects have been proposed,which will provide theoretical references and a basis for its future development and applications.
出处
《食品科学》
EI
CAS
CSCD
北大核心
2010年第17期392-396,共5页
Food Science
基金
"十一五"国家科技支撑计划重大项目(2008BAD94B09)
关键词
金属硫蛋白
理化性质
生理功能
重金属
metallothionein
physico-chemical characteristics
physiological function
heavy metal
