摘要
多发性骨髓瘤(MM)是浆细胞恶性克隆性疾病,尽管常规化疗和放疗可使部分患者病情缓解,但不能使患者治愈。大剂量化疗联合造血干细胞移植提高了患者的完全缓解率、无瘤生存率和总生存率,使MM的疗效取得了突破性的进展。
Multiple myeloma (MM) is a largely incurable B-cell hematologic malignancy. Although some patients treated with traditional therapies, such as chemotherapy and radiotherapy, can enter a remission, the disease remains incurable. One of the biggest improvements in the treatment of MM is the use of high-dose chemotherapy followed by stem cell transplantation, which have resulted in an improved remission rate, diseasefree survival and overall survival.
出处
《国际肿瘤学杂志》
CAS
2010年第9期706-709,共4页
Journal of International Oncology
关键词
多发性骨髓瘤
干细胞移植
治疗
Muhiple myeloma
Stem cell transplantation
Therapy