摘要
目的:探讨血清总胆汁酸(TBA)水平与肝实质病变的关系。方法:对102例慢性肝炎患者作肝活检,观察肝组织病理分级分期及划分慢性肝炎病理程度,并检测血清TBA、白蛋白(ALB)、总胆红素(TBil)、谷丙转氨酶(ALT)。结果:肝组织炎症轻度(G1-2,S0-2)、中度(G3,S1-3)、重度(G4,S4)的TBA水平(x±s)分别为(16.74±13.34)μmol/L、(72.25±68.49)μmol/L和(186.34±96.18)μmol/L,呈重度>中度>轻度状态。轻度组和中度组与重度组比较均为P<0.01。结论:慢性肝炎血清TBA水平与肝组织炎症程度具有良好正比关系,对判断肝实质病变具有重要临床价值。
Objective：To explore the relationship between the level of serum total bile acid（TBA）and liver parenchyma lesion.Methods：102 patients with chronic hepatitis were performed liver biopsy in which inflammation degree of liver tissue and corresponding pathological degree were observed,and serum TBA, serum total bilirubin （TBil） and serum alanine aminotransferase （ALT） were detected.Results：The degree of hepatic tissue was slight（G1-2,S0-2）,medium（G3,S1-3） and severity（G4,S4）,and in which TBA were respectively（16.74±13.34）umol/L,（72.25±68.49）umol/L and（186.34±96.18）umol/L.There was statistical significance among the degree of lightnees, mediun and severity （P〈0.01）.Conclusion：The result suggests there is good proportional relation between the level of serum TBA and the inflammation degree of liver tissue in patients with chronic hepatitis, which is important clinical value to evaluateing the inflammation degree of liver tissue.
出处
《甘肃医药》
2010年第5期487-488,共2页
Gansu Medical Journal
关键词
慢性肝炎
胆汁酸
肝病理
chronic hepatitis
TBA
hepatic pathology
