摘要
提出用矩阵形式表示一组核酸序列的方法．以大肠杆菌ＳＤ序列（在起始密码子ＡＴＧ前－１～－２５位点的２５个碱基范围内）为例给出了表示各位点单碱基、相邻双碱基、相邻三碱基出现的矩阵形式，并计算了体现序列的保守性、关联性的Ｍ（ｌ）值，发现大肠杆菌ＳＤ序列保守性，相邻双碱基。
The method of the matrix representation for DNA sequences is provided.The matrixes that form the probabilities of the bases (single base,neighbor 2 base,3 base) in SD region (in region of -1 to -25 sites before ATG codon) for E.coli DNA sequences are given.The values of M(l) reflected conservative character and correlation character are calculated.We find that the conservative character of SD region of E.coli genes,the correlation characters of some elements (neighbor 2 base,3 base) are positive correlated to the genes expression level.
出处
《内蒙古大学学报（自然科学版）》
CAS
CSCD
1999年第3期329-334,共6页
Journal of Inner Mongolia University：Natural Science Edition
基金
国家自然科学基金
关键词
矩阵表示
保守性
基因表达水平
DNA
SD序列
Matrix representation
conservative character
SD region
genes expression level
