摘要
间充质干细胞具有强大的免疫调节能力和促进组织修复的巨大潜能。在急性胰腺炎的发病过程中,间充质干细胞能够抑制T、B淋巴细胞及多种炎性因子,并能"归巢"至损伤胰腺,促进损伤胰腺组织修复,参与了急性胰腺炎的病理生理过程。本文将对间充质干细胞在急性胰腺炎病程中的作用作一综述。
Recent studies have shown that mesenchymal stem cells(MSCs) have immunomodulatory properties and tissue repairing potential.In the process of acute pancreatitis,MSCs suppress T and B cells and a variety of inflammatory factors,and the homing to injuried pancreas to promote pancreatic tissue repairing.MSCs play an important role in pathophysiolgical progresses of acute pancreatitis.The review is on the effect of MSCs on acute pancreatitis.
出处
《基础医学与临床》
CSCD
北大核心
2010年第10期1109-1111,共3页
Basic and Clinical Medicine
基金
南京军区卫生重大科研专项(08Z029)
关键词
间充质干细胞
急性胰腺炎
免疫调节
修复
mesenchymal stem cells
acute pancreatitis
immunomodulation
repair