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抵抗素与动脉粥样硬化的研究进展

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摘要 抵抗素是一种新的脂肪细胞因子,它最初是由美国科学家Steppan等人在筛查噻唑烷二酮类(TZDs)药物下调的基因时首先发现的.作为一种促炎因子,抵抗素可以通过导致内皮功能失调,促平滑肌增殖迁移,促巨噬细胞的脂质沉积,导致脂质代谢紊乱等途径,促进动脉粥样硬化的发生与发展.
作者 李霞 刘志跃
出处 《医学信息(下旬刊)》 2010年第9期13-13,15,共2页 Medical information
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