短暂性脑缺血发作患者多种凝血相关指标的变化被引量：7

Serum levels of some coagulant indexes in transient ischemic attacks patients

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摘要目的研究短暂性脑缺血发作患者vWF,FⅧ:C及各种凝血相关指标的变化极其临床意义。方法检测并分析70例短暂性脑缺血发作患者及70例健康人血液vWF,FⅧ:C,FIB,ATⅢ,PT,APTT,TT和PT-INR水平。结果与健康对照组相比短暂性脑缺血发作患者的vWF和FⅧ:C水平较高。且vWF和FⅧ:C水平较高者更易进展为脑梗死。短暂性脑缺血发作患者与健康对照组的FIB,ATⅢ,PT,APTT,TT和PT-INR水平无明显差异。结论短暂性脑缺血发作患者凝血系统激活。检测血液vWF,FⅧ:C水平将有助于我们诊断和治疗短暂性脑缺血发作。 Objective To study serum levels and their clinical significance of vWF,FVIII：C and some other coagulant indexes in TIA patients.Methods The serum levels of vWF,FⅧ：C,FIB,ATⅢ,PT,APTT,TT and PT-INR were respectively detected in TIA group consisting of 70 patients and control group consisting of 70 health persons.Results Compared with the control,the serum levels of vWF and FVIII：C were higher in TIAs,and we found that the higher the levels were,the more likely to evolve to infarction.Whereas,there were no significant differences of FIB,ATIII,PT,APTT,TT and PT-INR between the two groups.Conclusion Coagulation process is activated in TIAs.Testing the serum levels of vWF and FⅧ：C helps to diagnose and treat TIAs.

作者陈蓓蕾李晓波袁成林

机构地区苏北人民医院神经科

出处《中风与神经疾病杂志》 CAS CSCD 北大核心 2010年第9期834-836,共3页 Journal of Apoplexy and Nervous Diseases

基金江苏省科技支撑计划(BE2009653)

关键词短暂性脑缺血发作凝血血管性假性血友病因子凝血因子Ⅷ:C Transient ischemic attacks Coagulative vWF FⅧ：C

分类号 R743.31 [医药卫生—神经病学与精神病学]

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