摘要
目的:调查美沙酮维持治疗(MMT)门诊患者抑郁、焦虑和失眠的检出率及相关因素。方法:采用流行病学现况调查设计,603位MMT门诊患者完成一般情况问卷、抑郁自评量表、焦虑自评量表和匹兹堡睡眠质量指数;用Logistic回归筛选抑郁、焦虑和失眠的相关因素。结果:样本抑郁、焦虑和失眠的检出率(95%置信区间)分别为:33.8%(30.1%,37.6%)、36.3%(32.5%,40.2%)和58.2%(54.3%,62.1%);三者的共病率依次为91.5%(抑郁共病焦虑)、78.7%(失眠共病焦虑)、60.7%(失眠共病抑郁)、56.0%(焦虑共病抑郁)、50.7%(抑郁共病失眠)和41.0%(焦虑共病失眠);抑郁与焦虑(OR=10.73)、失眠(OR=1.97)、无工作(OR=1.79)、无宗教信仰(OR=1.71)、MMT时间长(OR=1.04)和烫吸方式吸毒(OR=0.53)有关;焦虑与抑郁(OR=9.06)、无宗教信仰(OR=6.02)、失眠(OR=1.71)、无工作(OR=1.55)和MMT维持剂量高(OR=1.01)有关;失眠与抑郁(OR=2.02)、焦虑(OR=2.01)、无工作(OR=1.66)、MMT时间长(OR=1.03)和烫吸方式吸毒(OR=0.35)有关。结论:MMT门诊患者具有较高的抑郁、焦虑和失眠检出率及共病率;抑郁、焦虑和失眠发生除与吸毒特征、MMT治疗和社会文化因素有关外,均两两密切相关。
Objective：To investigate the detection rates and correlates of depression,anxiety and insomnia among methadone maintenance treatment （MMT） outpatients. Methods：Using cross-sectional survey design,we investigated 603 MMT outpatients with the Social-demographic Questionnaire,Self-rating Depression Scale,Self-rating Anxiety Scale and Pittsburgh Sleep Quality Index. Logistic regression was used to identify the associated factors. Results：The detection rates （95% confidence interval） for depression,anxiety and insomnia were 33.8% （30.1%,37.6%）,36.3% （32.5%,40.2%） and 58.2% （54.3%,62.1%）,respectively. Their comorbidity rates ranged from 41.0% to 91.5%. Depression was associated with anxiety （OR=10.73）,insomnia （OR=1.97）,unemployment （OR=1.79）,without religious belief （OR=1.71）,long MMT period （OR=1.04） and inhaling heroin （OR=0.53）. Anxiety was associated with depression （OR=9.06）,without religious belief （OR=6.02）,insomnia （OR=1.71）,unemployment （OR=1.55） and high MMT dose （OR=1.01）. Insomnia was associated with depression （OR=2.02）,anxiety （OR=2.01）,unemployment （OR=1.66）,long MMT period （OR=1.03） and inhaling heroin （OR=0.35）. Conclusion：The detection rates for depression,anxiety and insomnia are higher among MMT outpatients. Their occurrence correlates with each other and is related to drug-taking characteristics,MMT treatment and social-culture factors.
出处
《中国药物依赖性杂志》
CAS
CSCD
2010年第5期371-375,共5页
Chinese Journal of Drug Dependence
关键词
美沙酮维持治疗
门诊患者
抑郁
焦虑
失眠
相关因素
methadone maintenance treatment
outpatient
depression
anxiety
insomnia
correlates
