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溃疡性结肠炎发病机制及其诊断 被引量:31

The pathogenesis and diagnosis of ulcerative colitis
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摘要 溃疡性结肠炎是一病因未明的非特异性慢性结肠炎症性疾病,目前已知遗传、环境和感染、免疫因素与该病的发生和发展有关。该病的规范化诊断十分重要,强调临床、内镜、组织学、影像学以及其他检查的综合性诊断及排除性诊断。利用一切可靠的常规和新的诊断方法,排除病因可查的结肠炎,特别是感染性结肠炎。对初发病例,临床表现和结肠镜改变均不典型者,需要随访。注重全面评估疾病的分型、分布、严重和活动性及并发症,作为治疗选择与预后判断的依据。 Ulcerative colitis is a non-specific chronic inflammation of the colon with unknown etiology. Host genetic factor, environmental and infectious factors and imbalaneed immune regulations are well known to be related to the development and progression of this disease. Diagnosis of ulcerative colitis is based on clinical, endoscopic and histological criteria. Integrated and excluding diagnosis should be emphasized based on findings from clinicial manifestations, endoscopy,imaging study and other investigations. Colitis with known etiology, particularly the infectious colitis, can be ruled out" with use of all conventional and newly developed tools,Those with first onset but have atypical clinical manifestations or endoscopic findings should be followed up. Classification of type of the disease, extent, severity, activity and complications should all be considered in diagnosis of ulcerative colitis.
作者 宋璐 夏冰
出处 《中国实用内科杂志》 CAS CSCD 北大核心 2010年第11期1056-1058,共3页 Chinese Journal of Practical Internal Medicine
关键词 溃疡性结肠炎 发病机制 ulcerative colitis pathogenesis diagnosis
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