摘要
结直肠癌是最常见的消化道恶性肿瘤之一.近年,以显微内镜分子成像技术诊断癌前病变和肿瘤逐渐成为研究的热点.随着对结直肠癌分子机制研究的不断深入,特异性分子靶向探针结合显微内镜技术,可有助于结直肠癌的早期诊断,在其指导下的分子靶向治疗有望成为治疗结直肠癌的一种新手段.本文就显微内镜分子成像技术在结直肠癌及其癌前病变诊断方面的研究进展作一综述.
Colorectal cancer is one of the most common malignant tumors of digestive system. In recent years, investigation concerning the application of microendoseopie molecular imaging technique in diagnosis of precancerous lesion and tumor has become a hot spot. With intensive study of molecular mechanisms of colorectal cancer, targeted specific probe incorporated with microendoscopic technique could help the early diagnosis of colorectal cancer, and the targeted therapy under its guidance might be a new approach for the treatment of eoloreetal cancer. This article reviewed the advances in study of microendoscopic molecular imaging technique in the diagnosis of colorectal cancer and precancerous lesion.
出处
《胃肠病学》
2010年第10期626-628,共3页
Chinese Journal of Gastroenterology
关键词
结直肠肿瘤
分子探针
显微镜检查
共焦
Colorectal Neoplasms
Molecular Probes
Microscopy, Confocal
