摘要
目的：提高氧氟沙星生物利用度，降低其不良反应。方法：以明胶、甘油为基质制备氧氟沙星阴道栓，建立其质量控制，并且对其进行临床观察。结果：本品制备工艺可行，质量控制能够控制本品的质量，临床疗效可靠，无不良反应。
OBJECTIVE:To increase the bioavailability and reduce the adverse reaction of ofloxacin. METHODS:Ofloxacin vaginal suppository was prepared with gelatine and glycerine as materials.Its quality control was established,and ofloxacin vaginal suppository was observed in clinic.RESULTS:The preparation of ofloxacin vaginal suppository was practicable,quality control be able to control the quality of this product.The clinical therapy of ofloxacin vaginal suppository was reliable with none of adverse reactions.CONCLUSIONS:It may be used in clinic.
出处
《中国医院药学杂志》
CAS
CSCD
北大核心
1999年第4期203-204,共2页
Chinese Journal of Hospital Pharmacy
关键词
氧氟沙星
阴道栓
质量控制
研制
ofloxacin,vaginal suppository,quality control,clinical observation
