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急性胰腺炎细胞因子的动态变化及其意义 被引量:8

Significance of the dynamics of cytokins in the plasma in patients with acute pancreatitis
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摘要 目的探讨细胞因子在急性胰腺炎病程发展中的作用。方法应用ELISA法检测28例急性胰腺炎病人血液中肿瘤坏死因子(TNFα),可溶性白介素2受体(SIL2R),白介素6(IL6)。结果急性胰腺炎病人血液中TNFα,SIL2R,IL6含量明显增高(与正常对照组相比P<0.05),并与临床症状的变化相一致。结论细胞因子参与了急性胰腺炎病程发展的过程,并且是组织损伤的重要因素。 Objective To study the effect of cytokins in the development of acute pancreatitis(AP). Methods TNF α, SIL 2R and IL 6 in plasma in 28 patients with AP and 20 healthy persons were determined Elisa method. Results The level of TNF α, SIL 2R and IL 6 in plasma in acute pancreatitis patients was significantly higher than that in control group ( P <0.05), and the changes were related to the clinical symptoms. Conclusions Cytokines are involved in the development of acute pancreatitis make up are the important factors for tissue injury.
出处 《中国普通外科杂志》 CAS CSCD 1999年第3期212-215,共4页 China Journal of General Surgery
关键词 胰腺炎 急性 肿瘤坏死因子 白细胞介素 PANCREATITIS/BL ACUTE DISEASE TUMOR NECROSIS FACTOR/BL INTERLEUKIN 6/BL RECEPTORS, INTERLEUKIN 2/BL
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