期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

超级细菌及其感染治疗药物 被引量：3

Super bacteria and their treatment
在线阅读 下载PDF
导出
摘要 抗菌药物是治疗和控制感染性疾病的重要手段。然而,随着抗菌药物滥用现象的日益严重,各种超级细菌相继出现,人类又将再次面临"无药可医"的局面。本文介绍4种在临床上较具代表性的耐药菌株,对临床相关感染的治疗药物评价予以综述。 Antibacterial agents are the important drugs to treat and control the infectious diseases. Overuse of antibiotics can induce antibiotic-resistant bacteria. As ＂superbugs＂, which are far more dangerous than their antibiotic- sensitive relatives appeared, human will return to ＂no cure＂ situation. This review describes four resistant organisms and some related antibacterial agents.
作者 李禛如 钟倩
机构地区 中国医药工业信息中心
出处 《世界临床药物》 CAS 2010年第11期704-704,I0001-I0004,共5页 World Clinical Drug
基金 国家"重大新药创制"科技重大专项(2009ZX09309)
关键词 耐药菌 抗菌药物 应对措施 resistant organism antibacterials counter-measures
分类号 R978.1 [医药卫生—药品] R515 [医药卫生—内科学]
  • 相关文献

参考文献25

  • 1宗春辉,孙兰菊,李东华,朱广莉,吴尚为.MRSA分子流行病学研究[J].中国感染控制杂志,2010,9(2):85-88. 被引量：7
  • 2Barmerman TL, Hancock GA, Tenover FC, et al. Pulsedfield gel electrophoresis as a replacement for bacteriophage typing of Staphylococcus aureus [J]. J Clin Microbiol, 1995, 33 (3): 551-555.
  • 3Dalla Costa LM, Reynolds PE, Souza HA, et al. Characterization of a divergentn vand-type resistance element from the first glycopeptide-resistant strain of Enterococcus faecium isolated in Brazil [J]. Antimicrob Agents Chemother, 2000, 44 (12) : 3444-3446.
  • 4Arias CA, Reyes J, Zuniga M, et al. Multicentre surveillance of antimicrobial resistance in Enterococci and Staphylococci from Colombian hospitals, 2001-2002[J]. Andmicrob Chemother, 2003, 51 (1): 59-68.
  • 5Zhanel GG, Laing NM, Nichol KA, et al. Antibiotic activity against urinary tract infection (UTI) isolates of vancomycin- resistant Enterococci (VRE) : results from the 2002 north American vancomycin resistant Enterococci susceptibility study (NAVRESS) [J]. Andmi-crob Chemother, 2003, 52 (3) : 382-388.
  • 6杨会军,张丽霞.耐万古霉素肠球菌基因分型及耐药机制的研究进展[J].国外医学（微生物学分册）,2004,27(1):29-31. 被引量：3
  • 7宋秀杰,刘又宁,梁蓓蓓,白楠,蔡芸,刘浩,陈桂云,王睿.20种抗菌药物对肺炎链球菌的体外抗菌活性研究[J].中国药物应用与监测,2010,7(1):20-23. 被引量：12
  • 8Adam J, Schurek KN, Nichol KA, et al. Molecular characterization of increasing fluoroquinolone resistance in Streptococcus pneumoniae isolates in Canada, 1997 to 2005[J]. Antimicrob Agents Chemother, 2007, 51 (1): 198-207.
  • 9Deshpande LM, Sader HS, Debbia E, et al. Emergence and epidemiology of nuoroquinolone-resistant Streptococcus pneumoniae strains from Italy: report from the SENTRY antimicrobial surveillance program (2001 - 2004) [J]. Diagn Microbiol Infect Dis, 2006, 54 (3) : 157-164.
  • 10张小江,徐英春,原英,谢秀丽,窦红涛,赵颖,王澎,朱任媛,王辉,陈民钧.替加环素等14种抗菌药物对多重耐药菌的体外抗菌活性研究[J].中国感染与化疗杂志,2009,9(5):365-368. 被引量：46

二级参考文献98

  • 1刘又宁,陈民钧,赵铁梅,王辉,王睿,刘庆锋,蔡柏蔷,曹彬,孙铁英,胡云建,修清玉,周新,丁星,杨岚,卓建生,唐英春,张扣兴,梁德荣,吕晓菊,李胜歧,刘勇,俞云松,魏泽庆,应可净,赵峰,陈萍,侯晓娜.中国城市成人社区获得性肺炎665例病原学多中心调查[J].中华结核和呼吸杂志,2006,29(1):3-8. 被引量：790
  • 2吴本权,唐英春,张天托,张扣兴,朱家馨.万古霉素与β-内酰胺类联合对MRS的协同抗菌活性(英文)[J].中国抗生素杂志,2006,31(8):473-480. 被引量：4
  • 3阎红霞,殷小基,郭发良.耐甲氧西林金黄色葡萄球菌医院感染分析与预防措施[J].临床医学,2006,26(11):2-3. 被引量：7
  • 4Wyeth Pharmaceuticals Inc. Tygacil Product Insert Philadelphia, PA, USA[EB/OL]. http://www, tygacil, com, 2006 12 -19.
  • 5Bauer G, Berens C, Projan SJ, et al. Comparison of tetracycline and tigecycline binding to ribosomes mapped by dimethysulphate and drug directed Fe^2+ cleavage of 16S rRNA[J]. J Antimicrob Chemother, 2004, 53(4) :592-599.
  • 6Rice LB. Challenges in identifying new antimicrobial agents effective for treating infection with Acinetobaeter baumannii and Pseudomonas aeruginosa [J]. Clin infect Dis,2006, 43 (Suppl 2) : S100 S105.
  • 7Kelesidis T, Karageorgopoulos DE, Kelesidis I, et al. Tigecycline for the treatment of multidrug resistant Enterobacteriaceae : a systematic review of the evidence from microbiological and clinical studies[J]. J Antimicrob Chemother, 2008, 62(5) :895- 904.
  • 8Baudry PJ, Nichol K, DeCorby M, et al. Comparison of antimicrobial resistance profiles among extended-spectrum-betalactamase producing and acquired AmpC beta lactanase-producing Escherichia coli isolates from Canadian intensive care units[J]. AntimicrobAgentsChemother, 2008, 52(5):1846-1849.
  • 9Castanheira M, Sader HS, Deshpande LM, et al. Antimierobial activities of tigecycline and other broad speetrum antimicrobials tested against serine earbapenemase and metallo-β- laetamase-producing Enterobacteriaceae: Report from the SENTRY Antimicrobial Surveillance Program[J]. Antimicrob Agents Chemother, 2008, 52(2) :570- 573.
  • 10Capone A, D'Arezzo S, Visca P, et al. In vitro activity of tigecycline against muhidrug resistant Acinetobacter baurnannii[J]. J Antimierob Chemother, 2008, 62(2) :422-425.

共引文献118

同被引文献38

  • 1张伟.普通感冒不能滥用抗生素[J].中国中医药现代远程教育,2009,7(6). 被引量：5
  • 2石和鹏,冯彩虹,金洁,刘浚.新型1β-甲基碳青霉烯类抗生素厄他培南[J].中国新药杂志,2004,13(12):1172-1175. 被引量：14
  • 3中华人民共和国卫生部,国家中医药管理局,总厅卫生部.抗菌药物临床应用指导原则[S].卫医发[2004] 285号.
  • 4Kumarasamy KK,Toleman MA,Walsh TR,et al. Emergence of a new antibiotic resistance mechanism in India, Pakistan, and the UK:a molecular,biological, and epidemiological study[J]. Lancet Infect Dis,2010,10(9) :597-602.
  • 5Yong D,Toleman MA,Giske CG, et al. Characterization of a new metallo-betadactamase gene, bla ( NDM-1 ), and a novel erythro mycin esterase gene carried on a unique genetic structure in Kleb- siella pneumoniae sequence type 14 from India[J]. Antimicrob A- gents Chemother, 2009,53 (12) : 5046-5054.
  • 6Castanheira M,Deshpande LM, Mathai D, et al. Early dissemina- tion of NDM-1- and OXA 181-producing Enterobacteriaeeae in In dian hospilals: report from the SENTRY Antimicrobial Surveil lance Program, 2006 2007 [J]. Antimicrob Agents Chemother, 2011,55(3):1274-1278.
  • 7Deshpande P, Rodrigues C, Shetty A, et al. New Delhi Metallo-be ta lactamase(NDM 1) in Emerobacteriaeeae: treatment options with earbapenems compromised [ J ]. J Assoc Physicians India, 2010,58(1) :147-149.
  • 8Martinez JL. Antibiolies and antibiotic resistance genes in natural environments[J]. Science,2008,321(5887) :365-367.
  • 9I.aupland KB, Church DL, Vidakovich J, et al. Community onset extended-spectrum beta-lactamase (ESBL) producing Escherichia coil:importance of international travel[J]. J Infect, 2008,57(6) : 441-448.
  • 10Ambler RP. The slructure of beta laetamases[J]. Philos Trans R Soc I.ond B Biol Sei,1980,289(1036):321-331.

引证文献3

二级引证文献12

世界临床药物
2010年 第11期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部