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焦炉作业工人早期生物检测指标的研究 被引量:3

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摘要 目的探讨焦炉逸散物对作业工人某些生化指标的影响。方法对某焦化厂86名生产工人和35名非接触者进行了末梢血某些免疫指标的测定,收集班后尿,并收集个人信息,使用碱水解-高效液相色谱法测定尿中1-羟基芘。结果 尿中1-羟基芘浓度呈炉顶>炉侧>炉底>对照组的趋势,与外暴露呈显著相关性(r=0.727,P<0.001);焦炉工血清中TNF-α水平明显高于非暴露人群,P<0.001;IgE水平略高于非暴露人群,P=0.05;焦炉工尿1-羟基芘水平与血清中TNF-α呈弱相关(r=0.316,P<0.001);血液检测发现焦炉工白细胞计数和血红蛋白含量均显著高于非暴露组,P<0.05。结论焦炉逸散物可致作业工人细胞免疫和体液免疫指标的改变。
出处 《毒理学杂志》 CAS CSCD 北大核心 2010年第5期374-377,共4页 Journal of Toxicology
基金 科技部社会公益研究专项项目(2005DE101439)
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