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鳖龙软肝片抗肝纤维化临床观察 被引量:10

Clinical study of Bielong Ruangan capsule on liver fibrosis
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摘要 目的观察鳖龙软肝片治疗慢性乙型肝炎肝纤维化患者的临床疗效。方法观察慢性乙型肝炎肝纤维化患者46例,随机分为治疗组(鳖龙软肝片组)23例,对照组(扶正化瘀胶囊组)23例。在常规保肝治疗基础上,两组分别加服鳖龙软肝片和扶正化瘀胶囊。疗程24周。对患者治疗前后Fibrolndex积分和疗效进行比较。结果两组Fibrolndex积分值经重复测量的方差分析,组间比较F=0.00,P>0.05;治疗前后时间效应F=29.59,P<0.01。两组疗效差异无统计学意义(P>0.05)。结论鳖龙软肝片有抗肝纤维化的功效。在判断慢性乙型肝炎肝纤维化病程及动态监测过程中,结合Fibrolndex指数模型能更好地评估鳖龙软肝片治疗慢性乙型肝炎肝纤维化的疗效。 Objective To evaluate the clinical effect of Bielong Ruangan capsule on patients with liver fibrosis of hepatitis B.Methods The 46 patients with chronic hepatitis B were randomly divided into the treatment(BRC) group(n=23) and control(FHC) group(n=23) treated with BRC and FHC respectively on the basis of conventional treatment,24 weeks one course.The Fibrolndex scores and curative effects before and after treatment were compared.Results Fibrolndex integral measured by repeated analysis of variance between groups F=0.00,P0.05;the time effects before and after treatment F=29.59,P0.01,there was no significant difference between two groups(P0.05).Conclusion Bielong Ruangan capsule is effective for hepatic fibrosis.In determining the course of liver fibrosis in chronic hepatitis B and dynamic monitoring of the process,Bielong Ruangan capsule combined with Fibrolndex index model is assessed better for patients with chronic hepatitis B.
出处 《湖南中医药大学学报》 CAS 2010年第9期181-183,共3页 Journal of Hunan University of Chinese Medicine
关键词 乙型肝炎 肝纤维化 鳖龙软肝片 临床观察 鳖甲 黄芪 山棱 chronic hepatitis B liver fibrosis Bielong Ruangan capsule clinical study turtule shell Astragalus mongholicus
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