摘要
目的:探讨血清孕酮(P)和妊娠相关蛋白-A(PAPP-A)在早期诊断异位妊娠(EP)和稽留流产中的价值。方法:选择确诊的宫内早孕、异位妊娠患者各40例及稽留流产患者20例,用酶联免疫吸附法检测血清P、PAPP-A水平。结果:与宫内早孕组比较,异位妊娠和稽留流产组血清P和PAPP-A水平低于宫内早孕组,差异有统计学意义(P<0.05),异位妊娠组和稽留流产组之间比较,差异无统计学意义(P>0.05);同一孕周时,正常宫内早孕者血清PAPP-A的含量高于EP患者,且差异有统计学意义(P<0.05)。结论:血清孕酮、妊娠相关血浆蛋白A检测有助于异位妊娠和稽留流产的早期诊断。
Objective：To explore the value of serum progesterone and pregnancy associated plasma protein-A（PAPP-A） in early diagnosis of ectopic pregnancy and missed abortion.Methods：40 cases with early intrauterine pregnancy,40 cases with ectopic pregnancy and 20 cases with missed abortion were selected,their serum levels of progesterone and PAPP-A were detected by ELISA.Results：The serum levels of progesterone and PAPP-A in ectopic pregnancy group and missed abortion group were significantly lower than those in early intrauterine pregnancy group（P〈0.05）,but there was no significant difference between ectopic pregnancy group and missed abortion group（P〉0.05）;at the same gestational weeks,the serum level of PAPP-A in early intrauterine pregnancy group was significantly higher than that in ectopic pregnancy group（P〈0.05）.Conclusion：The detection of serum progesterone and PAPP-A is helpful for early diagnosis of ectopic pregnancy and missed abortion.
出处
《中国妇幼保健》
CAS
北大核心
2010年第34期5051-5053,共3页
Maternal and Child Health Care of China
关键词
孕酮
妊娠相关血浆蛋白-A
异位妊娠
稽留流产
Progesterone
Pregnancy associated plasma protein - A
Ectopic pregnancy
Missed abortion
