摘要
目的通过比较肠易激综合征患者(IBS)与正常对照组之间、不同性别、不同年龄、职业焦虑、抑郁方面的差异,探讨精神心理因素在IBS发病中的作用。方法采用焦虑自评量表(SAS)、抑郁自评量表(SDS)对142例IBS患者及100例健康人进行评分,并做相关统计分析。结果 IBS患者的焦虑、抑郁评分显著高于正常对照组(48.72±9.98 vs 41.44±5.83;53.17±12.57 vs41.97±6.59;P<0.01);女性IBS患者焦虑、抑郁积分显著高于男性IBS患者(50.27±10.57 vs 46.48±8.65;55.03±12.58 vs 50.48±12.17;P<0.05);患者的自觉症状越重,其焦虑抑郁的发生率越高(40.9%,39.7%,70.2%,P<0.05;45.5%,46.6%,85.1%,P<0.01)。而不同年龄、不同职业的IBS患者之间焦虑抑郁并无显著差异。结论 IBS患者中焦虑、抑郁较正常人多见,且与症状的严重程度相关,其中女性IBS患者焦虑及抑郁较男性患者更为常见。
Objective To discuss psychiatric and psychological factors in the onset of irritable bowel syndrome by comparing the levels of anxiety and depression between IBS patients and healthy subjects and discuss their association with sex,age,occupation.Methods Anxiety and depression were assessed by self-rating anxiety scale and self-rating depression scale in IBS patients and healthy subjects respectively.Results The scores of anxiety and depression were significantly higher in IBS patients than those in healthy subjects（48.72±9.98 vs 41.44±5.83;53.17±12.57 vs 41.97±6.59;P 0.01）.The scores of anxiety and depression were significantly higher in female patients than those in male IBS patients（50.27±10.57 vs 46.48±8.65;55.03±12.58 vs 50.48±12.17;P 0.05）.The more severe patients felt,the more anxiety and depression happened（40.9%,39.7%,70.2%,P0.05;45.5%,46.6%,85.1%,P 0.01）.However,there was no significant correlation of anxiety and depression with age and occupation of IBS patients.Conclusion Anxiety and depression occur more frequently in IBS patients than those in healthy subjects,and correlate with the severity of IBS symptom.Anxiety and depression are more frequently seen in female than that in male patients with IBS.But there was no significant link of anxiety and depression with ages and occupations of IBS patients.
出处
《中国医科大学学报》
CAS
CSCD
北大核心
2010年第11期947-949,952,共4页
Journal of China Medical University
关键词
肠易激综合征
焦虑
抑郁
irritable bowel syndrome
anxiety
depression
