摘要
目的了解医院铜绿假单胞菌和鲍氏不动杆菌的分布特征及其对常用抗菌药物的耐药性,以便指导临床抗菌药物的合理使用。方法回顾性分析2007年1月-2008年12月分离的铜绿假单胞菌和鲍氏不动杆菌的药敏结果,剔除重复菌株。结果铜绿假单胞菌和鲍氏不动杆菌临床分布以ICU最多,分别为24.8%、35.7%,分离标本以痰液最多分别为68.5%、72.7%;铜绿假单胞菌对阿米卡星、头孢哌酮/舒巴坦的耐药率较低分别为20.5%、20.2%;鲍氏不动杆菌对氨苄西林/舒巴坦、头孢哌酮/舒巴坦的耐药性较低为16.2%和10.2%。结论铜绿假单胞菌和鲍氏不动杆菌在临床的分离率不断增加,耐药性不断增强,必须加强耐药性监测,根据药敏结果合理用药。
OBJECTIVE To investigate the antibiotic resistance of Pseudomonas aeruginosa and Acinetobacter baumannii in our hospital and to guide the rational use of antibiotic.METHODS The antibiotic resistance of P.aeruginosa and A.baumannii during from Jan 2007 to Dec 2008 in our hospital was reviewed retrospectively.The repeated strains were kicked out.RESULTS The 24.8% of P.aeruginosa and 35.7% of A.baumannii were from intensive care unit（ICU）.The 68.5% of P.aeruginosa and 72.7% of A.baumannii were examined from sputum.The resistance rate of P.aeruginosa to amikacin and cefoperazone/sulbactam were 20.5%,and 20.2%,and that of A.baumannii to ampicillin/sulbactam and cefoperazone/sulbactam was 16.2% and 10.2%.CONCLUSION With the increasing isolation and resistance rates of P.aeruginosa and A.baumannii,the surveillance for drug resistance should be emphasized.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2010年第23期3781-3783,共3页
Chinese Journal of Nosocomiology
关键词
铜绿假单胞菌
鲍氏不动杆菌
抗菌药物
耐药性
Pseudomonas aeruginosa
Acinetobacter baumannii
Antimicrobial agents
Resistance
