摘要
目的观察剖宫产术围手术期应用抗菌药物对术后感染的预防效果。方法选择2009年10月-2010年5月行剖宫产的160例产妇为研究对象,随机分为研究组和对照组,每组80例;研究组于手术前30 min给予头孢唑林,术后不再使用;对照组术前、术中未用药,术后给予头孢唑林,共4 d;观察并比较术后两组发热、感染等情况。结果研究组术后最高体温为(37.25±0.33)℃,退热时间为(1.44±1.17)d,均显著小于对照组,组间比较差异有统计学意义(P<0.05);研究组产褥病发生率、切口感染率和宫腔感染率分别为12.50%、3.75%和3.75%,均显著低于对照组,组间比较差异有统计学意义(P<0.05)。结论剖宫产术围手术期应用抗菌药物能够有效预防术后感染,且剂量小、疗程短,优于术后用药。
OBJECTIVE To observe the effect of perioperative use of antibiotics in cesarean section for preventing postoperative infection.METHODS A total of 160 puerperas who received cesarean section from Oct 2009 to May 2010 were randomly divided into study group and control group,with 80 cases in each group.Puerperas in study group were given once intravenous cefazolin 1g 30 min before surgery.No cefazolin was used after surgery;while puerperas in control group were given intravenous cefazolin 1g,for 2 times a day after surgery,together used for 4 days with no medication before surgery.Fever and infection of the two groups were observed and compared after surgery.RESULTS The postoperative maximum body temperature was（37.25±0.33）℃ and fever time was（1.44±1.17）d in study group,and they were significantly lower than the control group,the differences between groups were statistically significant（P0.05）;the puerperal morbidity,incision infection rate and intrauterine infection rates were 12.5%,3.75% and 3.75%,respectively in study group and they were significantly lower than the control group,the differences between groups were statistically significant（P0.05）.CONCLUSION Perioperative use of antibiotics cesarean section can effectively prevent postoperative infection with low dose and short course,it is superior to postoperative medication.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2010年第24期3988-3989,共2页
Chinese Journal of Nosocomiology
关键词
剖宫产
围手术期
抗菌药物
术后感染
Cesarean section
Perioperative period
Antibiotics
Postoperative infection
