摘要
本工作研制一种具有大气压接口的单四极杆质谱仪。该仪器具有三级真空系统,与大气相邻的第一级真空接口基于加热的不锈钢毛细管设计;在第二级真空腔中采用射频高压驱动的方式远距离传输离子;第三级腔体放置四极杆和电子倍增器分离和探测离子,使用自制的控制系统控制仪器。基于此仪器,实现了大气压下电喷雾离子源、介质阻挡放电离子源离子化样品的检测,通过第一级腔体中的源内碰撞诱导解离获得了样品的二级子离子,增强了单四极杆质谱仪的定性能力。该仪器结构简单、成本低,可用于液相色谱-质谱联用分析和原位分析。
An atmospheric pressure interface-quadrupole mass spectrometer was developed.It used a three-chamber vacuum system,which the first vacuum interface was designed based a heated stainless steel capillary,and used a square quadrupole ion guide to transmit ions in the second stage vacuum,used a quadrupole mass filter and a multiplier to analyze and detect ions in the third stage vacuum,and used the home-built control system.Used the instrument,realized the detection of ions generated through the electrospray and dielectric barrier discharge ionization in the atmospheric environment,and daughter ions through the in-source collision-induced dissociation in the first vacuum chamber which improved the qualitative performance.The instrument is simple and low cost,can be used to LC/MS and in-situ analysis.
出处
《质谱学报》
EI
CAS
CSCD
2010年第6期337-341,共5页
Journal of Chinese Mass Spectrometry Society
基金
国家科技支撑计划(2006BAK03A21
2009BAK58B03)
创新方法工作专项(2008IM040200)资助
关键词
大气压接口
四极杆质谱仪
电喷雾离子源
介质阻挡放电离子源
源内碰撞诱导解离
atmospheric pressure interface
quadrupole mass spectrometer
electrospray
dielectric barrier discharge ionization
in-source collision-induced dissociation
