期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

非离子表面活性剂囊泡作为眼用制剂载体的研究进展 被引量：2

在线阅读 下载PDF
导出
摘要 由非离子表面活性剂在溶液中自发形成的囊泡结构是继脂质体后具有更多优良特性的药物载体。眼部给药的特殊性和局限性使得有必要开发新型给药系统,而非离子表面活性剂囊泡作为一种新型眼用药物载体,可以改善传统眼部给药的诸多问题,在眼部给药中显示出了广阔的应用前景。查阅国内外文献,本文简要综述了囊泡的性质及其作为药物载体在眼用制剂中的特点、评价和应用等。
作者 王志钢 臧琛 李慧 张保献
机构地区 中国中医科学院中药研究所
出处 《中成药》 CAS CSCD 北大核心 2010年第12期2144-2147,共4页 Chinese Traditional Patent Medicine
基金 中国中医科学院自主选题资助(Z02069) 重大新药创制(2009ZX0930-005-05)
关键词 非离子表面活性剂囊泡 眼部给药系统 药物载体 研究进展
分类号 R944 [医药卫生—药剂学]
  • 相关文献

参考文献19

  • 1Schoenwald RD. Ocular Pharmacokinetics. In: Zimmerman TJ. Textbook of Ocular Pharmacology [ M]. New York: Lippincott- Raven Publishers, 1997 : 119-138.
  • 2Sultana Y, Aqil M, Ali A, et al. Advances in the topical ocular drug delivery [J]. Expert Rev Ophthalmol, 2007,2 ( 2 ) : 309- 323.
  • 3Baillie A J, Florence A T, Hume L R, et al. The preparation and properties of niosomes: non-ionic surfactant vesicles [J]. J Pharrn Pharmacol, 1985,37( 12 ) :863-868.
  • 4Hao Yongmei, Zhao Fenglin, Li Na, et al. Studies on a high encapsulation of colehicine by a niosome system [J]. Int J Pharm, 2002,244:73-80.
  • 5Uchegbu I F, Vyas S P. Non-ionic surfactant based vesicles( niosomcs) in drug delivery [J]. Int J Pharm, 1998,172:33-70.
  • 6Carafa M, Santucci E, Lucania G. Lidocaine-loaded non-ionic surfactant vesicles : characterization and in vitro permeation studies [J]. lnt J Pharm. 2002. 231 : 21-32.
  • 7Kaur I P, Garg A, Singla A K, et al. Vesicular systems in ocular drug delivery: an overview [ J ]. Int J Pharm,2004,269:1-14.
  • 8Guinedi A S, Mortada N D, Mansour S, et al. Preparation and evaluation of reverse-phase evaporation and multilamellar niosomes as ophthalmic carriers of Acetazolamide [ J ]. Int J Pharm,2000, 306(1-2) :71-82.
  • 9Vangala A V, Rasul S R. Incorporation of acetazolamide into niosome using a novel pH gradient technique [J]. Pharm Chem J, 2006, 26 : 66-73.
  • 10Manosroi A, Wongtrakul P, Manosroi J, et al. Characterization of vesicles prepared with various non-lonic surfactants mixed with cholesterol [ J ]. Colloids Surf, B : Biointerfaces, 2003,30 : 129- 138.

同被引文献27

  • 1Balwant Rai,Jasdeep Kaur,Maria Catalina.Anti-oxidation actions of curcumin in two forms of bed rest:oxidative stress serum and salivary markers[J].Asian Pacific Journal of Tropical Medicine,2010,3(8):651-654. 被引量：9
  • 2许东航.阿霉素纳米制剂克服肿瘤多药耐药作用的研究[D].中国博士学位论文全文数据库,2008.
  • 3Muzzadupo R, Tavano L, Trombino S, et al. Niosomes from alpha, ome- ga-trioxyethylene-bis ( sodium 2-dodecyloxy-propylenesulfonate) : prep- aration and characterization [ J ]. Colloids Surf B Biointerfaces,2008,64 (2) :200-207.
  • 4Mahor S, Gupta PN, Rawat A, et al. A needle-free approach for topical immunization : antigen delivery via vesicular carrier system ( s ) [J]. Curr Med Chem,2007,14 (27) :2898-2910.
  • 5Muller D, Foulon M, Bonnemain B, et al. Niosomes as carriers of radio- paque contrast agents for X-ray imaging[J]. Microencapsul,2OO0,17 (2) :227-243.
  • 6Yang DB, Zhu JB, Huang ZJ, et al. Synthesis and application of poly ( ethylene glycol ) -cholesterol ( Chol-PEG ( m ) ) conjugates in physico- chemical characterization of nonionie surfactant vesicles, Colloids Surf B Biointerfaces[ J]. 2008,63 (2) : 192-199.
  • 7Huang Y, Chen J, Chen X, et al. PEGylated synthetic surfactant vesi- cles (Niosomes) : novel carriers for oligonucleotides[ J]. Mater Sci Ma- ter Med,2008,19(2) :607-614.
  • 8Fang JY, Hong CT, Chiu WT, et al. Effect of liposomes and Niosomes on skin permeation of enoxacin [J]. Int J Pharm ,2001,219 (1-2) :61 - 72.
  • 9Azeem A, Anwer MK, Talegaonkar S. Niosomes in sustained and tar- geted drug delivery : some recent advances [J]. Drug Target, 2009,17 (9) :671-89.
  • 10Alvi IA, Madan J, Kausb.ik D, et al. Comparative study of transfer- somes,liposoroes, and Niosomes for topical delivery of 5-fluorouracil to skin cancer cells : preparation, characterization, in-vitro release, and cytotoxicity analysis[J]. Anticancer Drugs ,2011,22( 8 ) :774-82.

引证文献2

二级引证文献7

中成药
2010年 第12期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部