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根据NCCN指引在基层医院治疗老年恶性肿瘤贫血的临床观察 被引量:5

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摘要 目的:探讨在基层医院应用NCCN指引综合治疗老年恶性肿瘤贫血的可行性及其对患者生存质量的影响。方法:确诊为恶性肿瘤中晚期老年患者并行化放疗后的病例共104例,根据治疗方法不同分为对照组与治疗组。其中对照组按传统的常规贫血治疗方法,治疗组以NCCN指引为治疗依据,对贫血原因、贫血程度、全身脏器功能状况及可能的治疗风险/获益予以评估,根据患者放化疗后血红蛋白(Hb)的水平,在常规支持对症治疗的基础上,(1)对于Hb<110g/L的患者,考虑给予促红细胞生成素治疗;(2)对于Hb<100g/L的患者,给予促红细胞生成素治疗。分别以Hb水平及生存质量变化情况作为评价指标。结果:治疗后复查患者Hb,治疗组的Hb水平较对照组明显提高(P<0.05);患者的生存质量治疗组明显提高的例数较对照组多(P<0.05)。结论:根据NCCN指引在基层医院综合治疗老年恶性肿瘤贫血具有可行性,能明显改善患者的生存质量。
出处 《实用医学杂志》 CAS 北大核心 2010年第23期4336-4338,共3页 The Journal of Practical Medicine
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