摘要
目的了解药品不良反应(ADR)发生的原因及规律,为临床合理用药提供参考。方法回顾性汇总100例ADR,分析患者年龄、性别、用药过程及不良反应发生情况。结果 100例患者中,男46例,女54例;60岁以上患者33例;涉及药物45种;单一用药38例,联合用药62例。抗菌药物引起的ADR居首位,占57.28%;皮肤及软组织损害最多,占40.68%;静脉给药是发生ADR的主要途径。结论临床应注意抗菌药物的应用,并尽量避免药物合用及静脉给药,以降低ADR发生率。
Objective To understand the causes and law of occurrence of adverse drug reactions（ADR） to provide reference for rational drug use in clinic.Methods A hundred cases of ADR were retrospectively summarized and analyzed on age,sex,drug use process and the occurrence of adverse reactions.Results Among 100 cases of ADR,there were 46 males and 54 females,33 patients aged over 60 years.Forty-five different kinds of drugs were involved.Sixty-two cases were drug combination.Antibacterial-induced ADR stood first on the list,which accounting for 57.28%.The cases of skin and soft tissues damages were maximum,accounting for 40.68%.Intravenous administration was the main route to ADR occurrence.Conclusion Antibacterials use should be paid more attention to in clinic.Drug combination and intravenous administration should be avoided as much as possible.
出处
《中国药业》
CAS
2011年第1期45-46,共2页
China Pharmaceuticals
关键词
药品不良反应
监测
分析
adverse drug reaction
monitoring
analysis
