摘要
目的根据CD4 T淋巴细胞计数评估HIV感染者手术并发症发生率的关系。方法回顾性分析上海公共卫生临床中心2009年1月-2010年3月收治的60例HIV阳性手术患者,按照不同CD4 T淋巴细胞计数分为A(CD4<100 cell/μl)、B(100 cell/μl<CD4<300 cell/μl)和C(CD4>300 cell/μl)三组。结果三组间术前白蛋白、血红蛋白、白细胞数量差异无统计学意义;A组术前HIV感染相关性并发症发生率为40%(6/15),术后甲级愈合率为66.7%(10/15),乙级愈合率为33.3%(5/15),手术死亡率为13.3%(2/15);其余二组Ⅰ类和Ⅱ类手术切口术前均无感染相关性并发症,术后伤口愈合均达到甲级,无手术死亡。结论 CD4 T淋巴细胞计数对HIV阳性患者的手术风险评估有重要意义,当CD4 T淋巴细胞计数<100 cell/μl时手术死亡率和感染性并发症发生率明显增加。
Objective To assess the relationship between postoperative infective complications and the different CD4 counts in patients with human immunoddficiency virus （HIV） infection. Methods The clinical materials of 60 cases with positive HIV coming from Shanghai Public Health Clinical Center from January 2009 to March 2010 were analyzed retrospective. CD4 T cell counts were divided into A（ CD4 counts 〈 100 cell/μl） , B（ 100 cell/μl 〈 CD4 counts 〈 300 cell/μl） and C（ CD4 counts 〉 300 cell/μl） groups. Results The preoperative albumin, hemoglobin,white blood cell count were no significantly different among the three groups. In group A ,6 of 15 cases （40%） had preoperative HIV infection-associated complication, 10 cases （66.7%） had primary closure,cases（33.3% ） had secondary closure,and 2 cases（ 13.3% ） died. The patients in other two groups of had no preoperative H1V infection-associated complication;all wounds had primary closure and there was no died case. Conclusion The CD4 cell count is important for the operation risk evaluation in HIV positive patients. Patients with a CD4 cell count of less than 100 probably are at greater risk of developing a postoperative infection and mortality during the postoperative period.
出处
《中华全科医学》
2011年第1期7-8,共2页
Chinese Journal of General Practice
基金
上海市公共卫生重点学科资助项目(08GWZX0103)
关键词
HIV
CD4计数
感染性并发症
Human immunoddficiency virus
CD4 cell count
Infective complications
