摘要
目的:研究黄芪丹参对小鼠免疫系统的药理作用,为临床应用提供实验依据。方法:将50只健康KM小鼠分为5个实验组,分别为空白对照组,阳性对照组,黄芪丹参高剂量组(1.00 g/ml)、中剂量组(0.50 g/ml)、低剂量组(0.25 g/ml),连续灌胃给药14 d后,进行小鼠碳粒廓清试验,测定小鼠巨噬细胞的碳粒廓清指数K和吞噬指数α;测定小鼠脾脏系数、胸腺系数和肝脏系数。结果:黄芪丹参提取液可提高小鼠腹腔巨噬细胞的廓清能力和吞噬速度,提高小鼠机体免疫能力。结论:实验证明黄芪丹参有增强小鼠免疫功能的作用。
Objective： To study the pharmacology of Membranaceus and Salvia on the immune system of mice and provide experimental basis for clinical application.Methods： 50 KM mice were randomly divided into 5 groups： control group,model group,Membranaceus and Salvia decoction high dose group（1.00 g/ml）,medium dose group（0.50g/ml）,low dose group（0.25 g/ml）.After 14 days continuous oral administration,detect the carbon clearance index and phagocytic index.Meanwhile,weigh the liver,spleen and thymus and calculate the index of each immune organs.Results： Membranaceus and Salvia decoction could significantly increase the peritoneal macrophages and phagocytic clearance capacity,enhanced the immune system of mice.Conclusion： Membranaceus and Salvia decoction can increase the immune function of mice.
出处
《中国医药导报》
CAS
2011年第2期23-24,共2页
China Medical Herald
关键词
黄芪
丹参
碳粒廓清
免疫功能
Membranaceus
Salvia
Carbon clearance
Immune function
