摘要
目的：评价中药复方大承气汤联合西医保守常规疗法治疗粘连性肠梗阻的临床疗效。方法：全面搜集以复方大承气汤联合西医保守常规疗法治疗粘连性肠梗阻相关的随机对照或半随机对照试验文献,对入选文献进行Jadad评分,质量评价,运用Review Manager 4.2.8统计相关数据作异质性检验、Mete分析、漏斗图分析和敏感性分析得出系统评价。结果：16篇文献符合纳入标准,复方大承气汤实验组与单纯保守常规疗法对照组有组间均衡性。Meta分析显示合并总有效率RR=1.30,其95%可信区间为1.24~1.36,菱形位于垂线右侧（z=11.15,P〈0.00001）,差异有统计学意义。结论：从统计结果分析,可认为联合复方大承气汤治疗粘连性肠梗阻疗效优于（西医）保守常规疗法,但所纳入的文献质量普遍偏低且样本量偏小,势必影响结果的论证强度,故尚需更多高质量的随机对照试验,提供高质量的证据。
Objective：To evaluate the clinical effects of Chinese medicine Potent Purgative Decoction with Additions combination conventional therapy in treatment of adhesive ileus.Methods：Based on the databases getting from medical literatures relating to Potent Purgative Decoction with Additions in treatment of adhesive ileus,which conducted by randomized controlled trials（RCT）or semi-randomized controlled trials.Then made a quality evaluation by Jadad scoring method,and took statistics of the correlated data with the methods of heterogeneity test,Meta analysis,filler-graph analysis and sensitivity analysis by Review Manager 4.2.8.Results：16 articles were included into the system evaluation.The baseline characteristics of the experiment group were similar to the control group.The total effective rate comparison relative risk（RR）to merge equaled 1.30,95% confidence interval（CI）was（1.24~1.36）.Rhombus located at the right of the perpendicular（z=11.15,P0.00001）.The results have Statistically significant difference.Conclusion：Our systemic evaluation shows the clinical effects of combination Potent Purgative Decoction with Additions is better than that of conservative routine treatment in treatment of adhesive ileus.However the quality of literatures needs to be improved which will influence the argumentation intensity of the conclusion.So more high-quailty RCTs are needed to provide high-quailty proof.
出处
《辽宁中医药大学学报》
CAS
2011年第2期113-116,共4页
Journal of Liaoning University of Traditional Chinese Medicine
基金
成都医学院创新性实验基金资助项目(CX2010020)
关键词
复方大承气汤
粘连性肠梗阻
系统评价
potent purgative decoction with additions
adhesive ileus
system evaluation
