摘要
目的:探讨慢性肾脏病基础上的急性肾衰竭(A/C)的发病情况、临床特点及预后。方法:对确诊为A/C的93例患者的基础肾脏病、ARF原因、转归等进行分析。结果:在导致A/C的诸多病因中,青壮年组与中老年组有明显的差异,青壮年组以恶性高血压(30.00%)、原发病活动(26.67%)等为主要病因,而中老年组以肾毒性药物(30.30%)、严重感染(30.30%)等常见。在93例A/C患者中有17例与药物相关(18.28%)。基础肾脏病中,以慢性肾小球肾炎、原发性肾病综合征、狼疮性肾炎较为常见。在原发病活动中以狼疮性肾炎为主(84.62%)。在93例A/C患者中有33例患者进行血透治疗(35.48%),治疗后有18例(54.54%)患者脱离透析。出院时4,1例(44.09%)患者血肌酐恢复至正常水平(Scr<133μmol/L)。结论:A/C并不少见,经过积极治疗后,大部分患者的肾功能好转,因此,早期正确的诊断和治疗对A/C的预后具有十分重要的意义。
Objective：To explore the incidence and clinical characteristics and prognosis of acute renal failure.Methods：Clinical data of 93 patients diagnosed as A/C were collected and the cause of acute renal failure（AFR）,relationship between cause and underlying renal diseases and factors affecting prognosis were analyzed.Results：Factors of A/C for the patients with different age are different.The main factors were drugs with renal toxicity（30.30%） and severe infection（30.30%） in aged patients,while they were malignant hypertension（30.00%）,activity of primary disease（26.67%） in young patients.Among 93 cases,17 patients＇ aggravations were related to drugs（18.28%）.In the basic kidney diseases,chronic glomerulonephritis,primary nephritic syndrome and loupus nephritis are very common.Loupus nephritis accounts for 84.62% in the activity of primary disease.Among 93 cases,33 cases（35.48%） needed renal replacement therapy,and 8 of them did not need dialysis any more after treatment.Serum creatinine returned to normal level（Scr 133umol/L）in 41 patients（44.09%） when discharged.Conclusion：A/C is a very common disease and after reasonable treatment,most patients＇ renal function can be improved,so early correct diagnosis and treatment are very important.
出处
《牡丹江医学院学报》
2010年第6期26-29,共4页
Journal of Mudanjiang Medical University
关键词
肾脏病
慢性
肾衰竭
急性
病因
预后
Kidney disease
chronic
Renal failure
Acute
Etiology
Prognosis
